Q6C7U7
Gene name |
TRM44 (YALI0D25212g) |
Protein name |
tRNA (uracil-O(2)-)-methyltransferase |
Names |
|
Species |
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) |
KEGG Pathway |
yli:YALI0D25212g |
EC number |
2.1.1.211: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6C7U7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6C7U7-F1 | Predicted | AlphaFoldDB |
No variants for Q6C7U7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6C7U7 | |||||
No associated diseases with Q6C7U7
9 regional properties for Q6C7U7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | B-box-type zinc finger | 91 - 132 | IPR000315 |
| domain | Zinc finger, RING-type | 15 - 59 | IPR001841 |
| domain | B30.2/SPRY domain | 280 - 494 | IPR001870 |
| domain | SPRY domain | 348 - 493 | IPR003877 |
| domain | Butyrophylin-like, SPRY domain | 314 - 331 | IPR003879-1 |
| domain | Butyrophylin-like, SPRY domain | 430 - 454 | IPR003879-2 |
| domain | Butyrophylin-like, SPRY domain | 462 - 480 | IPR003879-3 |
| conserved_site | Zinc finger, RING-type, conserved site | 30 - 39 | IPR017907 |
| domain | Zinc finger, RING-type, eukaryotic | 15 - 56 | IPR027370 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.211 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (uracil) methyltransferase activity | Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule. |
| tRNA (uracil-2'-O-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA methylation | The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. |
| tRNA nucleoside ribose methylation | The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFTPTDISGE | PSAVGTQWTP | YLSHPVDFGA | QHFLEAMLNV | ISQPNINSSV | IMRADIISDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LNMMPNIMGT | DKANEGFIFD | THEGPVDDDK | KDTDKDKNTP | VPPNLQDYEP | RQVEVTPCPV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KRVIVRRIIP | RNPQNDFSVN | QTCIVHSDKP | LWDSDGKETS | EGAKIAISYI | SHHDHPKSCP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YYLPCVKAVL | LYFDGSAISV | YYEKYTDYEL | SAEQEERCGR | IALHLLHTVF | RHSSGQKAGY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KKRVHHDMII | DRIKFQDRYI | YLKQKYAHSL | VSSWVESTDP | RKHVFEDLAI | AAFLIELWGQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MYKNKDDIYF | YDLGCGNGLL | VNILIKEGYV | GEGVDARARK | SWQTYEPEVT | QKLLEKIVVP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TVLLDQMVGQ | AQYLPPHAAE | KRLAEANGLA | TDPRVFQTAG | LPENAFLIGN | HSDELTCWIP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LMDRPFMVIP | CCSHALSGEK | KRFPPTSSDP | EEKSTYRSLV | GHVEQLSSKI | GWQVEKEYLR |
| 490 | 500 | 510 | 520 | ||
| IPSTRNAAVI | GRTRVEPQMN | IFEILYSEGG | GEGWVERARD | LCAKSPRNH |