Q6C7Q0

PR
Gene name
PFA4
Protein name
Palmitoyltransferase PFA4
Names
Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0D26345g
EC number
2.3.1.225: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

231-342 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6C7Q0

Entry ID Method Resolution Chain Position Source
AF-Q6C7Q0-F1 Predicted AlphaFoldDB

No variants for Q6C7Q0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6C7Q0

No associated diseases with Q6C7Q0

1 regional properties for Q6C7Q0

Type Name Position InterPro Accession
domain Palmitoyltransferase, DHHC domain 76 - 202 IPR001594

Functions

Description
EC Number 2.3.1.225 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
protein-cysteine S-palmitoyltransferase activity Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-

2 GO annotations of biological process

Name Definition
peptidyl-L-cysteine S-palmitoylation The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
protein targeting to membrane The process of directing proteins towards a membrane, usually using signals contained within the protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITFSNPWIG VIIPCIIIFT LSTFSAIYIL PHHVSNNELT LFICASAMVW ISYIIAIIVP
70 80 90 100 110 120
PGSPPKNYTP PENGMKMYCL KCKAYKPERT HHSKALGVCV LKMDHHCPWT NNTVGHRNMP
130 140 150 160 170 180
HFMRFLVWVD MTVGYLFIRL CIRIMKLWRD KHLPSYLFDK TEVILSIVFL PASFFVLFTV
190 200 210 220 230 240
GILTIRVFVN MCNGITQIES WECDRIESLV RRKIVTEERA EFPYDIELFT NIFNAVGSPL
250 260 270 280 290 300
TFWLPWGQPR GDGITFEKNE SGYTEEGEPL CWPPDHVDYD PENVPLQNLK DGLRRRGEEP
310 320 330 340
DCLLGGIGAG KMQAENDFYK RDHWRNVEGE KLADFGVEHT DI