Q6C1W9

PR
Gene name
TRM10
Protein name
tRNA (guanine(9)-N1)-methyltransferase
Names
tRNA methyltransferase 10, tRNA(m1G9)-methyltransferase, tRNA(m1G9)MTase
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0F12771g
EC number
2.1.1.221: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-143 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6C1W9

Entry ID Method Resolution Chain Position Source
AF-Q6C1W9-F1 Predicted AlphaFoldDB

No variants for Q6C1W9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6C1W9

No associated diseases with Q6C1W9

2 regional properties for Q6C1W9

Type Name Position InterPro Accession
domain tRNA methyltransferase TRMD/TRM10-type domain 128 - 297 IPR016009
domain tRNA methyltransferase TRM10-type domain 106 - 300 IPR028564

Functions

Description
EC Number 2.1.1.221 Methyltransferases
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
tRNA (guanine(9)-N(1))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine.
tRNA (guanine-N1-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
tRNA binding Binding to a transfer RNA.

1 GO annotations of biological process

Name Definition
tRNA N1-guanine methylation The process whereby a guanine in tRNA is methylated at position N1 of the guanine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVDVTEPVAP VEAVKETAGA SSATPEVDRT SEPHPKNPQN VPAPYNTKTA VIPEGMSKNE
70 80 90 100 110 120
WKKAQKKAIW ESKKDEIAAV KKEKKKAARK RKQLAISRGE IPAPIPQDER PPQTQLPISI
130 140 150 160 170 180
VLDCGFDEMM TQKEKVSLSA QVGRCYSANR KADARFDLTV NSFNKGLKDR FNNEMNKVHE
190 200 210 220 230 240
LWTNIKFVED DYTVPEDETA KSKLVYLSSD SDNVINELED GKTYIIGGIV DKGRYKNLCQ
250 260 270 280 290 300
DKASKQGLQT GRLPIADFIK LSGRKVLTTN HVFEILLKWT ELKDWKAAFE AVLPMRKLDP
310 320 330 340 350 360
ANYGRAHRRA RKKARLAEGA EGNDEEDDED DDDEEEEEEE SVSAEPEVVE TKAEVETDTE
370
TKAETEAETK A