Q6C0U8

PR
Gene name
CYM1 (YALI0F21615g)
Protein name
Mitochondrial presequence protease
Names
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0F21615g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

467-559 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6C0U8

Entry ID Method Resolution Chain Position Source
AF-Q6C0U8-F1 Predicted AlphaFoldDB

No variants for Q6C0U8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6C0U8

No associated diseases with Q6C0U8

4 regional properties for Q6C0U8

Type Name Position InterPro Accession
domain Peptidase M16, C-terminal 227 - 410 IPR007863-1
domain Peptidase M16, C-terminal 804 - 911 IPR007863-2
domain Peptidase M16, N-terminal 76 - 166 IPR011765
domain Peptidase M16C associated 487 - 733 IPR013578

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion intermembrane space
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRLKSLKKP VQAVVRRFAT TSAPTLSVGD NIHGFNVLRT KEIPEFDLQA TLLEHSTGAQ
70 80 90 100 110 120
HLHIARDDSN NVFSIGFKTN PPDRTGVPHI LEHTTLCGSE KYQVRDPFFK MLNRSLANFM
130 140 150 160 170 180
NAMTAQDYTF YPFATTNATD MKNLRDVYLD ATLKPLLREL DFSQEGWRLE NEDSKDKTSP
190 200 210 220 230 240
IILKGVVFNE MKGQMSNAAY AFYIRYLEKI YPSLNNSGGD PLVIPELTYE GLKKFHADHY
250 260 270 280 290 300
NPSNAKTFSY GDISVADHLE ALNAKFENCE ISKTPGNTER LPLEFSSAAE NTRIVEEGPI
310 320 330 340 350 360
DTLLDTSKQH KMSMSWLMGS PKDIYESFCV KIISSLLIDG HSSPLHQKLI DSGLGSSYSP
370 380 390 400 410 420
NTGLDSAPGA NIFSVGLQGV TESDLTKVET VILDTIKTTV AEGFDKGRID GLLHQTELAR
430 440 450 460 470 480
KDQNAKFGMA LMNGVLPGWF NQVDPLEALE WNSVLDRFNK DMEADPEFLQ KVMKKYLLDN
490 500 510 520 530 540
KYFHFQMNPN PDYEKNVQEK EDEILTDKLA KLTESDKEEI FETGANLEKM QEEPENLDCL
550 560 570 580 590 600
PTLHVSDIPR SKPRVALEHT KNPYPIQWRL APTNGLTYFH SISSLEGLPH EYYPFLPLFT
610 620 630 640 650 660
SSLTFLGTKD KTMGQLEDEI KLNTGGLDFS VSCSSSPLSL PSSQLNFAMD GVALDKNVET
670 680 690 700 710 720
MFGLFQELLR NTDFTNVEKL KTMIAASTAN LSNALAQSGH SFAMLRAASD ISPVKKIDDI
730 740 750 760 770 780
LGGVAQVRFL SELAAKSEQQ LVDEVIPKLQ EIAKFALTRE QRFAVTCGQD MQTKNDELVR
790 800 810 820 830 840
KFAESFETNE SPFNISSLSI PMTTPTSTLF KLPFQVNYAG IAIPGVPYTH ADGAPLQVLA
850 860 870 880 890 900
NMLTHKHLHR EIREKGGAYG GGASYNPTDG FFSYYSYRDP NLERTLQTCQ EAGEWSVKKD
910 920 930 940 950 960
WSSSDLQEAK LSLFQRIDAP ISVKSEGMAL YANGLTYEQR EKRRRQLLDV AVDDVKRVAK
970 980
QYLVNPSGYS VAALGPGYET MDKKKWTVLE