Q6BZG7
Gene name |
PKAR (DEHA2A01474g) |
Protein name |
cAMP-dependent protein kinase regulatory subunit |
Names |
PKA regulatory subunit |
Species |
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
KEGG Pathway |
dha:DEHA2A01474g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6BZG7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6BZG7-F1 | Predicted | AlphaFoldDB |
No variants for Q6BZG7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6BZG7 | |||||
No associated diseases with Q6BZG7
7 regional properties for Q6BZG7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cyclic nucleotide-binding domain | 213 - 331 | IPR000595-1 |
| domain | Cyclic nucleotide-binding domain | 333 - 450 | IPR000595-2 |
| domain | cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 5 - 43 | IPR003117 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 240 - 256 | IPR018488-1 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 276 - 293 | IPR018488-2 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 360 - 376 | IPR018488-3 |
| conserved_site | Cyclic nucleotide-binding, conserved site | 397 - 414 | IPR018488-4 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cAMP-dependent protein kinase complex | An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| cAMP binding | Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate). |
| cAMP-dependent protein kinase regulator activity | Modulation of the activity of the enzyme cAMP-dependent protein kinase. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of protein phosphorylation | Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTDNQYATEE | LNQLQKELVA | KNPIDVLQFC | ANYFNSKLEL | QRSQLWQQQN | KAKAAGINLF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSIDNVFNSD | GGAIMTTNKR | QPSFKSPFGD | NDPTSIDHHH | DDDPKEAPGA | SKQQNKAELF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGGFGVGKST | PSKPLQELDP | NDPSHSASQD | TDAAPPVPKS | KIPVAFNANR | RTSVSAEAMN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PNKFKSDSWK | PPINDLTAAQ | KVELSKTLGS | NFLFRQLDVS | SKKTVIEALG | KKEFKNGDEI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IKQGDEGDYF | YIIEKGTVDF | YVNGNQVNSS | GEGSSFGELA | LMYNSPRAAT | AVAASDTGVT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CWALDRQTFR | RILLERTFNR | RLMYEDFLKD | VKVLSSLSSQ | ERSKLADALS | TEIYHKGDKI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VKEGEQGENF | YFIESGSCQV | SKDGKGVLTK | LSKGDYFGEV | ALLNDLPRQA | TVEALDTVIV |
| 430 | 440 | 450 | |||
| ATLGKSGFSR | LLGPAVDILK | SQDPTANQGS | SN |