Q6BZE9

PR
Gene name
SNX4 (ATG24, DEHA2A01892g)
Protein name
Sorting nexin-4
Names
Autophagy-related protein 24
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
KEGG Pathway
dha:DEHA2A01892g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-159 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6BZE9

Entry ID Method Resolution Chain Position Source
AF-Q6BZE9-F1 Predicted AlphaFoldDB

No variants for Q6BZE9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6BZE9

No associated diseases with Q6BZE9

1 regional properties for Q6BZE9

Type Name Position InterPro Accession
domain Phox homology 116 - 249 IPR001683

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytosol
  • Preautophagosomal structure membrane ; Peripheral membrane protein
  • Endosome membrane ; Peripheral membrane protein
  • Endosome and other perivacuolar punctate structures
  • Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome membrane The lipid bilayer surrounding an endosome.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.

2 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSDDQFTSI QWDRDELGPN KETKVNKQET ITEDDEHHNN DNEDKDNDTT KSNEPENIQE
70 80 90 100 110 120
DDETKDDNEP TDSLILSKTG DENISNIESQ NEGDHIVGEP DVNQEPSSDS QTEAYEINVV
130 140 150 160 170 180
VTSPLRDLDS SSKPYISYLL TTATNHPSVM KLSTVKKEQG KEVVEITARR RYGDFRFLFD
190 200 210 220 230 240
CLSNDHPEVM MPPLPSKSNF KYLTGDTFST EFVHKRLHSL DRFVRFITCH KVLSQSSIFH
250 260 270 280 290 300
LFVSDSADWS TFQKNLKISK VGVQESDADK GNSSMTSNVV NKVVNEDLLT ETIMNFLTPS
310 320 330 340 350 360
KHKRETNKEI LEISDKLKKL YENLIKLDKI FTKLNKKNHD LSVDYEQFSQ QIMKLSVIQN
370 380 390 400 410 420
SSDETNEPTT PEINEQKQFA TNFKVFASSL SYFSDNWSNL HKYIDESFLV SLKDCAKYII
430 440 450 460 470 480
SLTNLIELQH NKKIDLQVLQ DYLNKAKSEL QGLGGSHNAP PNPIITHNNG GIVNNTTQLI
490 500 510 520 530 540
RDTLSTSATP NIGSSVTESK VTKLQNRITE LENEISVQSQ LVLDLTNKII NEEYPNWDKF
550 560 570 580
NKIELKESLL GLCNEEISFY KGLVDNWSDI ELKLLKRLDE LK