Q6BY27
Gene name |
DBP2 (DEHA2A12958g) |
Protein name |
ATP-dependent RNA helicase DBP2 |
Names |
|
Species |
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
KEGG Pathway |
dha:DEHA2A12958g |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6BY27
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6BY27-F1 | Predicted | AlphaFoldDB |
No variants for Q6BY27
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6BY27 | |||||
No associated diseases with Q6BY27
5 regional properties for Q6BY27
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 257 - 265 | IPR000629 |
| domain | Helicase, C-terminal | 326 - 486 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 129 - 299 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 124 - 327 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 105 - 133 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYNNNSDSY | GGGYNSYGGN | SYGGGGYGGG | RGGGRGGFGG | RGGGRYDERV | ELNTPEWDID |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SLPKFEKNFY | NEHPDVTARS | VQDVNAFRKE | HDMKCDGTDI | PKPITSFDEA | GFPDYVLKEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KQQGFPKPTS | IQCQGWPMAL | SGRDMVGIAS | TGSGKTLSYC | LPSIVHINAQ | PLLSPGDGPI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLVLAPTREL | AVQIQQECSK | FGSSSRIRNT | CVYGGAPKGQ | QIRDLARGVE | ICIATPGRLI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DMLETGKTNL | RRVTYLVLDE | ADRMLDMGFE | PQIRKIVDQI | RPDRQTLMWS | ATWPKEVQAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TRDYLNDPIQ | VTVGSLELAA | SHTITQLVEV | VTEFEKRDRL | IKHLETATAD | PEAKCLIFAS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TKRTCDEITN | YLRADGWPAL | AIHGDKQQGE | RDWVLKEFKT | GKSPIMVATD | VAARGIDVKG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ISYVINLDMP | GNIEDYVHRI | GRTGRAGSTG | TAVSFFTDNN | SKLGGDLCKI | MREANQTIPP |
| 490 | 500 | 510 | 520 | 530 | |
| ELMRFDRRSF | GSHIRYGRGG | GRGGFRGGRG | RGGFRGGRGG | YQSGSNSAPL | GNARRY |