Q6BX78
Gene name |
TRM8 |
Protein name |
tRNA (guanine-N(7)-)-methyltransferase |
Names |
Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase |
Species |
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
KEGG Pathway |
dha:DEHA2B05258g |
EC number |
2.1.1.33: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6BX78
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6BX78-F1 | Predicted | AlphaFoldDB |
No variants for Q6BX78
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6BX78 | |||||
No associated diseases with Q6BX78
No regional properties for Q6BX78
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6BX78 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.33 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA (guanine-N7-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine. |
| tRNA binding | Binding to a transfer RNA. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKIEATSKE | EKLRVQKEAE | ARRRAYRDLK | KEARQMQKEV | KFDTDDNSEL | PKKRFYRQRA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HSNPFSDHRL | EYPRSPDTMD | WSKFYPQYYD | SESKKMTSEV | EIADIGCGYG | GLLINLAPEF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PDKLLLGMEI | RVQVTQYVED | RIIALRNQYR | NELQNNYQNI | SVLRGNAMKF | LPNFFHKAQL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKMFFCFPDP | HFKQRKHKAR | IITNTLLAEY | AYVLKEGGII | YTITDVEDLH | NWMVKHLEEH |
| 250 | 260 | 270 | 280 | 290 | |
| PMFERLSKEW | EKQDKCVSIM | WNSTEEGKKV | TRNKGSKWVA | CFKRLPTPDD | CE |