Q6BVK1
Gene name |
TIM21 (DEHA2C02002g) |
Protein name |
Mitochondrial import inner membrane translocase subunit TIM21 |
Names |
|
Species |
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
KEGG Pathway |
dha:DEHA2C02002g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6BVK1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6BVK1-F1 | Predicted | AlphaFoldDB |
No variants for Q6BVK1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6BVK1 | |||||
No associated diseases with Q6BVK1
No regional properties for Q6BVK1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q6BVK1 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| TIM23 mitochondrial import inner membrane translocase complex | The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into mitochondrial matrix | The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKSISTLGIC | LRASQDLAKT | RPISLLSTRS | FANLTQGTST | YHSLSIRSIR | HNRLEARYTN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ILNRNILPYK | NYSTGTAPPP | PPPPPPPHDK | NAKGKFLFNR | IGRAFTFSLS | SVIVLGATCI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SVLVVYLILS | ELFLPSGDTR | TFNKAVRMLE | SNELAHEALG | FKKGQRVKAH | GEQHADKWAR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NRPAQSVRTR | GADGKDYLFM | KFQVESPSGK | YGTVTLEQVD | RTFWSSEFLY | IALDMPGNKR |
| 250 | 260 | 270 | |||
| IYIKEPKFQS | KKYVPKVGSL | ASNDGFLGLK | WGPKKDD |