Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q6BQ61

Entry ID Method Resolution Chain Position Source
AF-Q6BQ61-F1 Predicted AlphaFoldDB

No variants for Q6BQ61

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6BQ61

No associated diseases with Q6BQ61

6 regional properties for Q6BQ61

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 213 - 221 IPR000629
domain Helicase, C-terminal 291 - 438 IPR001650
domain DEAD/DEAH box helicase domain 89 - 255 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 84 - 282 IPR014001
domain RNA helicase, DEAD-box type, Q motif 65 - 93 IPR014014
domain DDX47/Rrp3, DEAD-box helicase domain 66 - 268 IPR044765

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVKVDGMIN KKSKTHSKKL DARALAEKIK KNALKQQAQE EPAKEENVAE NFDTVVDPTA
70 80 90 100 110 120
ELKFKSFNEL KLIPELLEAI QQMKFTKPTP IQSEAIPHAL EGKDIIGLAQ TGSGKTAAFA
130 140 150 160 170 180
IPILQALWEA QAAYYGLVLA PTRELAYQIK ETFDALGSSM GLRSVCIVGG MDMMDQARDL
190 200 210 220 230 240
MRKPHILVAT PGRIMDHLEH TKGFSLKNLK YLVMDEADRL LDMDFGPALD KILKIIPTQR
250 260 270 280 290 300
TTYLFSATMT NKIAKLQRAS LHNPVRVAVS NKYQTADNLV QSMMLVSDGY KNTYLIHLLN
310 320 330 340 350 360
EFLGKSIIIF TRTCAHSQRT ALLARILGFS AVPLHGQLTQ AQRLGSLNKF KAGKANILIA
370 380 390 400 410 420
TDVAARGLDI PSVDIVINYD IPTDSKAYIH RVGRTARAGK SGKSISLITQ YDLEMYLRIE
430 440 450 460 470
SVLGKKLPKD PSPSKAVLDT LHVHVDRASA EAIRQTKDFH EKRNPKKNRD DRDREER