Q6BMM5

PR
Gene name
CCR4 (DEHA2F04136g)
Protein name
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4
Names
Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
KEGG Pathway
dha:DEHA2F04136g
EC number
3.1.13.4: Exoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-244 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6BMM5

Entry ID Method Resolution Chain Position Source
AF-Q6BMM5-F1 Predicted AlphaFoldDB

No variants for Q6BMM5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6BMM5

No associated diseases with Q6BMM5

8 regional properties for Q6BMM5

Type Name Position InterPro Accession
repeat Leucine-rich repeat 335 - 356 IPR001611-1
repeat Leucine-rich repeat 358 - 379 IPR001611-2
repeat Leucine-rich repeat 381 - 402 IPR001611-3
repeat Leucine-rich repeat, typical subtype 336 - 355 IPR003591-1
repeat Leucine-rich repeat, typical subtype 356 - 379 IPR003591-2
repeat Leucine-rich repeat, typical subtype 381 - 401 IPR003591-3
domain Endonuclease/exonuclease/phosphatase 485 - 795 IPR005135
repeat Leucine rich repeat 4 336 - 372 IPR025875

Functions

Description
EC Number 3.1.13.4 Exoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
poly(A)-specific ribonuclease activity Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
RNA binding Binding to an RNA molecule or a portion thereof.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIPKYQQAQ VQGQQPNLQA QQILLQQLQQ GQSQQSQPSI GGSGSAGQFS QQDIYNDNIA
70 80 90 100 110 120
QQGLYQNSYQ RPVQAQQPPQ LQNIHQQQQF FPQQFSSQQQ NQPQASSLQQ YQQQQQQQQQ
130 140 150 160 170 180
QQQQQQQQQQ QQQQQQQQQQ PQIHLPQQYQ QSQGQQVPHQ PPHIQQQQFF NQQAAALQQQ
190 200 210 220 230 240
QQQQQQQQQQ QQQPAQKLNS INIENPNSIY WQHQQQLCQL SRNANIPHYY ARQYAANSRK
250 260 270 280 290 300
NKNPYSDVKT VSLIDATRSI VSALNEQENS KSNPGSATNS ALLQNKKLAQ DLDDDHLQEE
310 320 330 340 350 360
QRMRQKTQGR QLWCQLDLSG QGLVNLSPKL FQYDFLESLY LNNNKLTSVP PIVNKLRSLR
370 380 390 400 410 420
TLDLSHNRIN EVPSELGMCF NLRYLYLFDN NIKTLPNEFG NLIELLFLGI EGNPIDLKIA
430 440 450 460 470 480
NLVAEKGTKE LIAYLRDLKP SFSKPPPRQW LLLEDDGEII DPINNPDAYT NDNNNSDTND
490 500 510 520 530 540
TFTMMSYNTL CQHYATTKMY KYTPSWALEW GFRRAALQEE VLHFKSDLVC MQEVETRTFH
550 560 570 580 590 600
EFWVPVMQGF GYKGVFFNKT RSKTMSESDS KKVDGCATFY KTDKFELLHK QNFEYNSVCM
610 620 630 640 650 660
GSDKYKKTKD LFNRFMNKDN IALITYFNHI QTGEKILFVN THLHWDPAFN DVKTLQVGIL
670 680 690 700 710 720
LEELRTIMKK YHHTNSIDEI KNASMVICGD FNSTKENAVY QLFSTGAVSN HEDLEGRDYG
730 740 750 760 770 780
KFTDEGFRHS FKLKSAYDHV GELPFTTISP AFTDAIDYIW YSTPTLQVKG LLGKIDEEYS
790 800 810 820 830
SHCIGFPNAH FPSDHIPLVT KFQIKKSGGN KKPDFKPDFK PDFKSGSSRK T