Q6BL58

PR
Gene name
LOS1 (DEHA2F16192g)
Protein name
Exportin-T
Names
Exportin(tRNA), Karyopherin-beta, tRNA exportin
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
KEGG Pathway
dha:DEHA2F16192g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

560-630 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6BL58

Entry ID Method Resolution Chain Position Source
AF-Q6BL58-F1 Predicted AlphaFoldDB

No variants for Q6BL58

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6BL58

No associated diseases with Q6BL58

2 regional properties for Q6BL58

Type Name Position InterPro Accession
domain Exportin-1/Importin-beta-like 103 - 254 IPR013598
domain Exportin-T, C-terminal domain 322 - 997 IPR045546

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Shuttles between the nucleus and the cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
small GTPase binding Binding to a small monomeric GTPase.
tRNA binding Binding to a transfer RNA.

2 GO annotations of biological process

Name Definition
tRNA processing The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
tRNA re-export from nucleus The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDEQISKAVE IALSGTSDLV LKNQAFEFIN QIKSTEEGYK SCLDILLKSI NSNSPLNQEF
70 80 90 100 110 120
KFFILQVIDE NITKLNNEQL YELNSDLFQY LNYVINSNIN DPVYLKNKFA GIMGNLFCFT
130 140 150 160 170 180
YLSINPTFLK DLLALIADNN LIAIDIYSRI IIAVHTEISD KFISRSREVQ DRNNLLKDQI
190 200 210 220 230 240
RTNDMNLLVD NWQKILRNPE LIQHNNEVLN NFLKIIGYYI NWMEITLFIS NDFINIIFQY
250 260 270 280 290 300
LNKPDQRNET CLTLIEVISK KMKPLNKLEL ISLLNLTSII NSINNDDDLE FMENIAKLSN
310 320 330 340 350 360
QVGLELVIVL ESSELELFDS INQQFLNLWP SIFKFLSHEY DDISQQIFPF IQQYLLTCKK
370 380 390 400 410 420
FNQLASIELL SSLLNKIILK MKFDDDDDGT DDESTEQFNE VRLKLKTFQD TIAILKPELF
430 440 450 460 470 480
LEAIPIVINE SIFANVSDFD KVNWRNLELG LFELNTFTES LRNNLINLPK QEIGNSKPYV
490 500 510 520 530 540
LVQEFLIKLI NSDVVLKVDH PKIQLGFFEL IVRHYNFLNT NINNQEVILR ILELFSSPLG
550 560 570 580 590 600
LFNNSEKVRL RTWYLFFRFV KLTKPTLNNS SFIENLFIKL QPLLVIKAEL PTKDEDNDTV
610 620 630 640 650 660
ENGNFNNQLN LFESIGLLIS LLSVDISLKV RMIDLIFQPL FNDLENCISN KDKVNQQLIA
670 680 690 700 710 720
LQAHHSLMAI GTFARGYDYD YNNKYSAEIV GKINNASQVV LITLENFAKF EIIRDAARFS
730 740 750 760 770 780
FARFIPILNE EINNHLSKLV SIILAANNLK ISELTNFLNF LGQIVHNFQS NDNIYKLLND
790 800 810 820 830 840
LLSPLLDKIF SLLKYNGENN EYESMPDIIR DKESLKKSYM NFISAIITNH SSSLLITETN
850 860 870 880 890 900
KQKFPIILES FFVYAYNTSE PTVSKLAITQ LINVVSVMGG HGGKINDPQD KYGESLPPLE
910 920 930 940 950 960
GVDEYLMNKA VQLSFELPFQ KSEFDLKDAQ YRLVGQEIAS LLKTYQEKRG DEYLTFLSNY
970 980 990
LTNMGLSSEL MTDFCTNLVK VDQRAFKKYF ITFVTELKGK