Q6BKI8

PR
Gene name
EFM7
Protein name
Protein N-terminal and lysine N-methyltransferase EFM7
Names
Elongation factor methyltransferase 7
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
KEGG Pathway
dha:DEHA2F21604g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-63 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6BKI8

Entry ID Method Resolution Chain Position Source
AF-Q6BKI8-F1 Predicted AlphaFoldDB

No variants for Q6BKI8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6BKI8

No associated diseases with Q6BKI8

6 regional properties for Q6BKI8

Type Name Position InterPro Accession
repeat WD40 repeat 81 - 125 IPR001680-1
repeat WD40 repeat 131 - 176 IPR001680-2
repeat WD40 repeat 179 - 273 IPR001680-3
repeat WD40 repeat 295 - 332 IPR001680-4
repeat WD40 repeat 397 - 438 IPR001680-5
conserved_site WD40 repeat, conserved site 206 - 220 IPR019775

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
N-terminal protein N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
protein-lysine N-methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.

2 GO annotations of biological process

Name Definition
N-terminal peptidyl-glycine methylation The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
peptidyl-lysine dimethylation The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDDEFIDTG LFAEPEGFTP PPPPPHFAKY QRKNKTDPAE LNLRLVGKSP LWGHLLWNAG
70 80 90 100 110 120
VFTADYLDKH ADELVTGKDV LELGAAAGLP SLICGINKCN RVVCTDYPDP DLISNIQHNF
130 140 150 160 170 180
DHCQGLDLSK TVVKGFIWGA DAKPLMDDSE KEIQNEDKFD LVILSDLVFN HTEHLKLLKT
190 200 210 220 230 240
CRDTVKKNGK CLVVFSPHRP KLLENDLEFF RTCEDFQFKA EKIDLVTWKP MFEEDDESID
250
IRARVYSFFL VPQW