Q6BJ48
Gene name |
MUS81 (DEHA2G05214g) |
Protein name |
Crossover junction endonuclease MUS81 |
Names |
|
Species |
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii) |
KEGG Pathway |
dha:DEHA2G05214g |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6BJ48
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6BJ48-F1 | Predicted | AlphaFoldDB |
No variants for Q6BJ48
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6BJ48 | |||||
No associated diseases with Q6BJ48
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| crossover junction endodeoxyribonuclease activity | Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction). |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| metal ion binding | Binding to a metal ion. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA catabolic process, endonucleolytic | The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides. |
| DNA recombination | Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. |
| double-strand break repair | The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix. |
| meiotic cell cycle | Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGPPGDLKH | LFIEWLQEAA | INATKKGTKA | AILYNKALGS | VRNYPLPIND | PKTLKSVQFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDKTCIHLSK | KLEEYCKLNN | FELPVAFGGL | INGGVGEKRK | HEVSDTSNLP | DAKPKKQRKQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KQYIPRKRSG | GYAILLALYF | GDKKKTGLTK | EEIIQRATPY | SDKSFKSNPS | ANEFYSAWSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IKSLQTHDLV | DSSGRSSKSY | FLTEEGYELA | KQLKDAEGFE | SSPITNHIAD | LSFDNQVRVT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PDSSYSKISQ | QLDSSPLMKT | KNNKDRYGLG | PSRLSSTRER | ILDLSSSPRL | ISSPLKPKDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLRESLSSHN | STRPLQDRES | ISKAEDGINT | KTKARLVHDA | SKRIYDGTNY | DIWVPGEFEI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ILIIDNREIR | SQRDRDFFQT | RLTSLKVECD | VRPLSVGDVV | WTAKHKKTGR | EVILNYICER |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KRLDDLVSSI | KDGRFQEQKN | RLKKSGMKQF | YYLVEDVVTS | DMNKFGDMSD | AIQTAMSMTM |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TISNFYLKRF | KSIEDTIAFL | ASLTQVIKDQ | FAKNKTNLLV | LKARSIKNQA | EYSSLIAKFK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EKFENRSTSY | ECAHLFSTFQ | DSMGKTGMMT | VKETFILMLM | GIRGVSLERA | VAIQNRFKTP |
| 610 | 620 | 630 | 640 | 650 | |
| KNLIEFFFVE | NNHLSELDKK | QLMMDVFKNE | IGNKKIGKVL | SEKIYDVWGC | V |