Q6AZB0
Gene name |
Boc |
Protein name |
Brother of CDO |
Names |
Protein BOC |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:117606 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q6AZB0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1X4Y | NMR | - | A | 707-807 | PDB |
| 1X4Z | NMR | - | A | 591-698 | PDB |
| AF-Q6AZB0-F1 | Predicted | AlphaFoldDB |
1 variants for Q6AZB0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 1051 | R>Q | strain: C57BL/6 [UniProt] | No |
No associated diseases with Q6AZB0
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| axon | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. |
| axonal growth cone | The migrating motile tip of a growing nerve cell axon. |
| cell surface | The external part of the cell wall and/or plasma membrane. |
| growth cone | The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| neuronal cell body | The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| axon guidance | The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues. |
| cell projection organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. |
| cell-cell adhesion | The attachment of one cell to another cell via adhesion molecules. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| positive regulation of myoblast differentiation | Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. |
| regulation of striated muscle tissue development | Any process that modulates the frequency, rate or extent of striated muscle development. |
| smoothened signaling pathway | The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTCRRERPI | LTLLWILMAT | AGCLADLNEV | PQVTVQPMST | VQKLGGTVIL | GCVVEPPWMN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VTWRFNGKEL | NGSDDALGVF | ITRGTLVIAA | LNNHTVGRYQ | CVARMPAGAV | ASVPATVTLA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NLQDFKLDVQ | HVIEVDEGNT | AVIACHLPES | HPKAQVRYSV | KQEWLEASRD | NYLIMPSGNL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QIVNASQEDE | GMYKCAAYNP | VTQEVKTSGS | GDRLRVRRST | AEAARIIYPL | EAQTVIVTKG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QSLILECVAS | GIPPPRVTWA | KDGSSIAAYN | KTRFLLSNLL | IDTTSEEDSG | TYRCMASNGV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GDPGAAVILY | NVQVFEPPEV | TVELSQLVIP | WGQSAKLTCE | VRGNPPPSVL | WLRNAVPLTS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SQRLRLSRRA | LRVVSVGPED | EGVYQCMAEN | AVGSAHAVVQ | LRTARPDTTL | RPGRDTKPIA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ATPPMPPSRP | SRPDQMLREQ | PGLVKPPTSS | VQPTSLKCPG | EEQVAPAEAP | IILSSPRTSK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TDSYELVWRP | RHEGSSRTPI | LYYVVKHRKV | TNSSDDWTIS | GIPANQHRLT | LTRLDPGSLY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EVEMAAYNCA | GEGQTAMVTF | RTGRRPKPEI | VASKEQQIQR | DDPGASLQSS | SQPDHGRLSP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PEAPDRPTIS | TASETSVYVT | WIPRGNGGFP | IQSFRVEYKK | LKKVGDWILA | TSAIPPSRLS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VEITGLEKGI | SYKFRVRALN | MLGESEPSAP | SRPYVVSGYS | GRVYERPVAG | PYITFTDAVN |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ETTIMLKWMY | IPASNNNTPI | HGFYIYYRPT | DSDNDSDYKK | DMVEGDRYWH | SISHLQPETS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| YDIKMQCFNE | GGESEFSNVM | ICETKARKFS | GQPGRPPPLT | LAPPQPPPLE | TMERPVGTGA |
| 850 | 860 | 870 | 880 | 890 | 900 |
| MVARASDLPY | LIVGVVLGSI | VLIIVTFIPF | CLWRAWSKQK | HTTDLGFPRS | ALLSSSCQYT |
| 910 | 920 | 930 | 940 | 950 | 960 |
| MVPLEGLPGH | QANGQPYLGG | VSGRACVSRV | HGSRGCPAAT | VGCPGRKPQQ | HCPGELAQQR |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| EDTNSQLRQP | IVSNGYDLQN | QQVARGPQCA | SGVGAFLYTL | PDDSTHQLLQ | PQDCCHLQKQ |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| PVTTCQTAVR | RTSESPGLES | SWDPPYHSGP | RCCLGLVPVE | EVDSSDSCQV | GGGDWSSQHP |
| 1090 | 1100 | ||||
| SGTYTGQERG | MRFSPSPSVH | VSFETPPPTI |