Q6AYQ6

PR
Gene name
Mmadhc
Protein name
Cobalamin trafficking protein CblD
Names
CblD, Methylmalonic aciduria and homocystinuria type D homolog, mitochondrial
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:362134
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-164 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AYQ6

Entry ID Method Resolution Chain Position Source
AF-Q6AYQ6-F1 Predicted AlphaFoldDB

No variants for Q6AYQ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AYQ6

No associated diseases with Q6AYQ6

No regional properties for Q6AYQ6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6AYQ6

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
cobalamin metabolic process The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H3L0 MMADHC Cobalamin trafficking protein CblD Homo sapiens (Human) PR
Q99LS1 Mmadhc Cobalamin trafficking protein CblD Mus musculus (Mouse) PR
10 20 30 40 50 60
MAHVLCNRAR LVSYLPGFCS LVKRVINPRA FSTAGSSGSD ESHVATAPPD ICSRTVWPDE
70 80 90 100 110 120
TMGPFGPQDQ RFQLPGNIGF DCHLNGTASQ KKSQAHKTLP DVLAEPLSTE RHEFVMAQYV
130 140 150 160 170 180
NEFQDSNAPV EQEISSAETY FESARVECAI QTCPELLRRD FESLFPEVAN SKLMILTVTQ
190 200 210 220 230 240
KTEHDMTVWS EEVEVEREAL LEKFINGAKE ICYALRAEGY WADFIDPSSG LAFFGPYTNN
250 260 270 280 290
TLFETDERYR HLGFSVDDLG CCKVIRHGLW GTHVVVGSIF TNATADSHIM RKLSGD