Q6A000
Gene name |
Kiaa0753 (Mnr) |
Protein name |
Protein moonraker |
Names |
MNR |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:74477 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q6A000
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q6A000-F1 | Predicted | AlphaFoldDB |
No variants for Q6A000
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q6A000 | |||||
No associated diseases with Q6A000
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| centriolar satellite | A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome. |
| centrosome | A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| centriole replication | The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0. |
| cilium assembly | The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. |
| cytosolic ciliogenesis | The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm. |
| protein localization to centrosome | A process in which a protein is transported to, or maintained at, the centrosome. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KHM9 | KIAA0753 | Protein moonraker | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGPSQPASTC | VHLAPSLQLD | AMSDPRNLQP | QNQLQFNRNV | PTNPRNLAVR | YSCPHGIKIE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KLKHSYNELN | HGKDLDFKAG | NELSSSVSFS | VISEERLSYA | VHLAKRDVKR | RQFEEHVKDH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRSLPHSSHK | GMHTKVERKD | SKSQDVCHCS | HQPSRVSLSS | SGAKVYVYTS | QPGRSDLTVP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NSPPTHDPGL | QLQPRIEENK | NLWEQKGLLE | VQRLQKELSG | CIRKIEALTK | KDRLEEALDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DEEHRIRVRR | QEQAVRCARM | LYVLQQQVKE | IQEELDKLSP | QKIKHTKKSW | AVSRLAAAHR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AAIRALQVFV | TQFTDRGEHP | VPARCRELGS | LIRQLSLCSA | KLDADPSVPD | VVIDILQQIE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ALESLLEKKL | SPKKAKKCFT | EIRSRFPVGS | QKILERWPTV | LPKSERRHLV | TKETFPQETS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RPPVAKRLLA | AMCQPDGELQ | RLESEPDVLD | AHLLPEEAPR | IEDNGTDFKD | GTLTPAKPQA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VRRKALTGSM | PIRKKDTVES | ARPQQGLHIA | ERNRPNQPYS | KSRLQQTTVS | SRLKMNRQPM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KDHRAPWIPP | NPTSPPASPK | CAAWMKVKYS | PRDAAKEQSL | QQEDIHKESQ | LRGDAEQEAA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RLSWPDAESS | KRLKELEELE | AKEMERKQKQ | RLNWLEAETS | RRTKELDELK | AEEMDRLQKL |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SVSATQLADK | VEEAVLERLK | PLLIKAQRVN | SSVEANSHLK | DRPSRHAAAA | AQPAEQASDV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PFESRNIPQL | RDCLEDTAHE | LWARTQDKIL | GSETSARLGD | SKDSPDLETM | MLRMEEMEKY |
| 790 | 800 | 810 | 820 | 830 | 840 |
| QETVRQRYNK | IVYADPHLWM | HEERNDQNTP | AVSEGPLASH | PIKITKTATQ | KCPAVNILLE |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RPCNANSLDE | SVTTEEGSEK | REAPLPLSRE | DLHQRKGQTP | LSVPPRMRHS | IGAYCSRFEQ |
| 910 | 920 | 930 | 940 | 950 | |
| FLRIIAHEAI | GSFNPWLIAE | SFSDELVDEA | LGAVAAELQD | VCEDYAEAVF | TSEFLEAAA |