Q69ZS7
Gene name |
Hbs1l (Hbs1, Kiaa1038) |
Protein name |
HBS1-like protein |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:56422 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q69ZS7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1UFZ | NMR | - | A | 51-120 | PDB |
| AF-Q69ZS7-F1 | Predicted | AlphaFoldDB |
45 variants for Q69ZS7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389093976 | 34 | P>T | No | EVA | |
| rs3389091779 | 62 | N>S | No | EVA | |
| rs3389059793 | 64 | L>P | No | EVA | |
| rs3389087053 | 94 | D>E | No | EVA | |
| rs3389059751 | 107 | D>E | No | EVA | |
| rs257830897 | 124 | W>L | No | EVA | |
| rs3389059823 | 146 | R>W | No | EVA | |
| rs3389091974 | 175 | P>S | No | EVA | |
| rs3389089633 | 179 | S>Y | No | EVA | |
| rs13471458 | 188 | A>T | No | EVA | |
| rs13471459 | 200 | V>I | No | EVA | |
| rs3389087025 | 202 | S>F | No | EVA | |
| rs3389089684 | 211 | P>T | No | EVA | |
| rs3389095294 | 213 | S>Y | No | EVA | |
| rs3412866227 | 214 | A>V | No | EVA | |
| rs3389035432 | 227 | G>D | No | EVA | |
| rs3389091987 | 238 | K>R | No | EVA | |
| rs3389070205 | 243 | I>K | No | EVA | |
| rs3389100567 | 246 | K>* | No | EVA | |
| rs3389101378 | 270 | G>E | No | EVA | |
| rs3389035436 | 272 | S>R | No | EVA | |
| rs3412269889 | 327 | G>E | No | EVA | |
| rs3389089701 | 364 | V>A | No | EVA | |
| rs3389095232 | 427 | L>P | No | EVA | |
| rs3389087041 | 441 | P>Q | No | EVA | |
| rs260943720 | 452 | A>V | No | EVA | |
| rs3400948335 | 455 | Q>L | No | EVA | |
| rs3400748546 | 456 | S>A | No | EVA | |
| rs3400948389 | 456 | S>Y | No | EVA | |
| rs3400948366 | 457 | S>C | No | EVA | |
| rs3400612307 | 460 | T>A | No | EVA | |
| rs3389094031 | 462 | W>* | No | EVA | |
| rs3389092013 | 484 | K>N | No | EVA | |
| rs1134251020 | 491 | S>F | No | EVA | |
| rs3389065972 | 492 | D>N | No | EVA | |
| rs3410610794 | 501 | F>L | No | EVA | |
| rs3389092887 | 560 | I>F | No | EVA | |
| rs3389079497 | 564 | C>* | No | EVA | |
| rs3389091621 | 566 | F>I | No | EVA | |
| rs3413041831 | 583 | I>L | No | EVA | |
| rs3389066000 | 585 | V>D | No | EVA | |
| rs3389087035 | 585 | V>L | No | EVA | |
| rs3389091620 | 621 | S>N | No | EVA | |
| rs3389092893 | 628 | K>Q | No | EVA | |
| rs3389083715 | 682 | E>D | No | EVA |
No associated diseases with Q69ZS7
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARHRNVRGY | NYDEDFEDDD | LYGQSVEDDY | CISPSTAAQF | IYSRRDNPEE | EYGYEDLRES |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SNSLLNHQLS | EIDQARLYSC | LDHMREVLGD | AVPDDILTEA | ILKHKFDVQK | ALSVVLEQDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VQPWKEKSER | AVCAGQPSKG | KSVISRSSQS | ESEIVPKVAK | MTVSGKKQTM | GFEVPGLTSE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ENGLSVRAPH | KGPPGDDVSV | ASPNIPETGT | PKSALPPPSL | QTSEELGSTP | TPVRKSGKLR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QQIDVKAELE | KRQGGKQLLN | LVVIGHVDAG | KSTLMGHMLY | LLGNVNKRTM | HKYEQESKKA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GKASFAYAWV | LDETGEERER | GVTMDVGMTK | FETTTKVITL | MDAPGHKDFI | PNMITGAAQA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DVAVLVVDAS | RGEFEAGFET | GGQTREHGLL | VRSLGVTQLA | VAVNKMDQVN | WQQERFQEIT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GKLGHFLKQA | GFKESDVAFI | PTSGLSGENL | TARSQSSDLT | TWYKGMCLLE | QIDSFKPPQR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SIDKPFRLCV | SDVFKDQGSG | FCVTGKIEAG | YIQTGDRLLA | MPPNETCTAK | GITLHDEPVD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| WAAAGDHVNL | TLVGMDIIKI | NVGCIFCGPK | EPIKACTRFR | ARILVFNIEV | PITKGFPVLL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| HYQTVSEPAV | IKRLISVLNK | STGEVTKKKP | KLLTKGQNAL | VELQTQRPVA | LELYKDFKEL |
| 670 | 680 | ||||
| GRFMLRYGGS | TVAAGVVTEI | KE |