Q69HU0

PR
Gene name
copB
Protein name
Probable copper-transporting P-type ATPase B
Names
Species
Staphylococcus aureus
KEGG Pathway
EC number
7.2.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q69HU0

Entry ID Method Resolution Chain Position Source
AF-Q69HU0-F1 Predicted AlphaFoldDB

No variants for Q69HU0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q69HU0

No associated diseases with Q69HU0

2 regional properties for Q69HU0

Type Name Position InterPro Accession
ptm P-type ATPase, phosphorylation site 365 - 371 IPR018303
domain P-type ATPase, haloacid dehalogenase domain 345 - 612 IPR044492

Functions

Description
EC Number 7.2.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
metal ion binding Binding to a metal ion.
P-type monovalent copper transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEHHSHQEHE NHTSHGNHEH HHHGNFKSKF FISLIFAIPI IILSPMMGVK LPFQISFTGS
70 80 90 100 110 120
DWIVLILATI LFFYGGKPFL SGAKDEISTK KPGMMTLVAL GISVAYIYSL YAFYMNNFSG
130 140 150 160 170 180
SSTHTMDFFW ELATLILIML LGHWIEMNAV GNAGNALKKM AELLPNTAVK LIDNNQREEV
190 200 210 220 230 240
KISDIHIDDI VEVRAGESIP TDGIIVRGET SIDESLVTGE SKKVHKTHND DVIGGSINGS
250 260 270 280 290 300
GTVQVKVTAT GENGYLSQVM GLVNQAQNDK SKAELLSDKV AGYLFYFAVS IGLISFIVWM
310 320 330 340 350 360
LIQNNVDFAL ERLVTVLVIA CPHALGLAIP LVTARSTSIG AHNGLIIKNR ESVEIAQHID
370 380 390 400 410 420
YIMMDKTGTL TEGNFSVNHY ESFTDELNNE EILSLFASLE SNSNHPLATG IVDFAKGKNI
430 440 450 460 470 480
SYATPQEVNN IPGVGLEGTV DNKKLKIVNV SYLDKSNFDY NKEQFTNLAQ QGNSISYLIH
490 500 510 520 530 540
DRQVIGIIAQ GDKIKESSKQ MVSDLLSRNI TPVMLTGDNK EVAQTVAEEL GISDVHAQLM
550 560 570 580 590 600
PEDKESIIQD YQSNGSKIMM VGDGINDAPS LIRADIGMAI GAGTDVAIES GDVILVKSNP
610 620 630 640 650 660
SDIINFLSLS KNTMKKMVQN LWWGAGYNVI AVPLAAGILA SIGLILSPAV GAILMSLSTI
670
IVAINAFTLK LK