Q69024

PR
Gene name
gB
Protein name
Envelope glycoprotein B
Names
gB
Species
Guinea pig cytomegalovirus (strain 22122) (GPCMV)
KEGG Pathway
vg:14536657
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q69024

Entry ID Method Resolution Chain Position Source

No variants for Q69024

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q69024

No associated diseases with Q69024

2 regional properties for Q69024

Type Name Position InterPro Accession
domain Herpesvirus Glycoprotein B, PH-like domain 1 121 - 331 IPR035377
domain Herpesvirus Glycoprotein B, PH-like domain 2 333 - 430 IPR035381

Functions

Description
EC Number
Subcellular Localization
  • Virion membrane ; Single-pass type I membrane protein
  • Host cell membrane ; Single-pass type I membrane protein
  • Host endosome membrane ; Single-pass type I membrane protein
  • Host Golgi apparatus membrane ; Single-pass type I membrane protein
  • During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs
  • It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
host cell endosome membrane The lipid bilayer surrounding a host cell endosome.
host cell Golgi membrane The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.
host cell plasma membrane The plasma membrane surrounding a host cell.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
viral envelope The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
virion membrane The lipid bilayer surrounding a virion.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
virion attachment to host cell The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRPVRGIARS RILSCSWRGT WTSALTILYL GVYCESTTVT PTTVEDTTVS NGNHSDASRN
70 80 90 100 110 120
NTVIRNLTAS VDFSQRKLYP YRICSMSMGT DLVRFARTIQ CVPFNPRVNS EEGIMLIYKR
130 140 150 160 170 180
NILPYVFTAY TYQKELLFQR SYKYVTYDYL LGYSREFVAL PMWEIFLVNS RGQCYTSHQR
190 200 210 220 230 240
VIGADRYIAY HNDNEVNETM WLMRDDMGND DTYRYITVKE HARTPGSVWL YKETCSMNCI
250 260 270 280 290 300
VTKTKGKSKF PYDMFVLPSG VIVNISPFYN GSNGKTFREQ REKFHIWSNY SILKDFGSRA
310 320 330 340 350 360
LEARIVPKMA FYEREDVVIG WEVNDQSNVT CEMILWETVD RAIRTEYENA FHYVARTLTS
370 380 390 400 410 420
TFVENKYSPD NNLTEDDIKC FKNDAQKKIE EVFLRDYNET YDMDGNATYH VTTGGLVIVW
430 440 450 460 470 480
QGLKQKSLKA LEIAANESAV SATGSNSRRK RSLPDESTGD ISYAQLQFAY DTLRTYINQA
490 500 510 520 530 540
LGHIAEAWCL DQKRTAEVLH ELSKINPSNI LSAIFGVPVA ARVVGDVISL AKCIEVNQST
550 560 570 580 590 600
VLIKGDMRKF SDDGKLEGCY SRPVVWFSMK NSTEVRLGQL GEDNEILLGT HRMETCQTQD
610 620 630 640 650 660
YRIFVAGDIG YEFQQYVFTK KINLSEIDII DTMIALKTEP LENIDFKVLE LYSRDELAQA
670 680 690 700 710 720
NVFDLESIMR EYNYQKKRLD FVVERVINPI PPALKGLDEM MNGMGAIGKG IGEAVGAVGG
730 740 750 760 770 780
AIGSFIGALV TFVTNPFGAF VVFLFCVGCI TLVITVYRRQ RRAMQRPFDY FFPYASQTIT
790 800 810 820 830 840
SSVADSSIAV AYPGPEGTSG DAPPPYPGEA PYGYKDLSVD ADTRVSSSSA GAGADFNEED
850 860 870 880 890 900
AVRMLRAIKR LDDKKRQEIE KSSKDSASNK NSETRRRPGI MDRLRRRGGY QKLNTEDDVH
V