Q68XV9

PR
Gene name
aatA (RT0046)
Protein name
Probable aspartate/prephenate aminotransferase
Names
AspAT / PAT, Transaminase A
Species
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
KEGG Pathway
rty:RT0046
EC number
2.6.1.1: Transaminases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q68XV9

Entry ID Method Resolution Chain Position Source
AF-Q68XV9-F1 Predicted AlphaFoldDB

No variants for Q68XV9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q68XV9

No associated diseases with Q68XV9

2 regional properties for Q68XV9

Type Name Position InterPro Accession
binding_site Aminotransferases, class-I, pyridoxal-phosphate-binding site 236 - 249 IPR004838
domain Aminotransferase, class I/classII 32 - 392 IPR004839

Functions

Description
EC Number 2.6.1.1 Transaminases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
glutamate-prephenate aminotransferase activity Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.
L-aspartate:2-oxoglutarate aminotransferase activity Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

2 GO annotations of biological process

Name Definition
alpha-amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid.
biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSIISTRLNS IKPSPTLAVV KKTLELKKAG VNIIALGAGE PDFDTPDNIK EVAITSIKDG
70 80 90 100 110 120
FTKYTNVDGI PLLKQAIKNK FKRENNIDYE LDEIIVSTGG KQVIYNLFMA SLDKGDEVII
130 140 150 160 170 180
PVPYWVSYPD MVALSTGTPI FVNCGIENNF KLTVEALERS ITDKTKWLII NSPSNPTGAG
190 200 210 220 230 240
YNCKELENIA KTLRKYPNVN IMSDDIYEHI TFDDFKFYTL AQIAPDLKER IFTVNGVSKA
250 260 270 280 290 300
YSMTGWRIGY GAGSKALIKA MTVIQSQSTS NPCSISQMAA IEALNGTQDY IKPNALNFQK
310 320 330 340 350 360
KRDLALSILE KVIYFECYKP EGAFYLFVKC DKIFGTKTKS GKIIANSNHF SEYLLEEAKV
370 380 390
AVVPGVAFGL DGYFRISYAT SMQELKEACI RIKQACNTL