Q67T83

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Symbiobacterium thermophilum (strain T / IAM 14863)
KEGG Pathway
sth:STH125
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

823-903 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q67T83

Entry ID Method Resolution Chain Position Source
AF-Q67T83-F1 Predicted AlphaFoldDB

No variants for Q67T83

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q67T83

No associated diseases with Q67T83

8 regional properties for Q67T83

Type Name Position InterPro Accession
conserved_site SEC-C motif 881 - 899 IPR004027
domain SecA DEAD-like, N-terminal 6 - 384 IPR011115
domain SecA Wing/Scaffold 627 - 844 IPR011116
domain SecA, preprotein cross-linking domain 228 - 340 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 629 IPR014018
conserved_site SecA conserved site 482 - 497 IPR020937
domain SecA, C-terminal helicase domain 402 - 599 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALKILERIF GDYSAKVVKR HQRTVALINS LEPEMQKLSD AELAHKTVEF KERIARGETL
70 80 90 100 110 120
EQILPEAFAV VREASIRTTG RRPFDVQLIG GIVLHEGNIA EMKTGEGKTL VAAMPLYLNA
130 140 150 160 170 180
LLGRGCHLVT VNDYLAKVGR DDIGRIYRFL GMSCGLIVHG LTSAQRREAY NCDITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MAMHPQDMVH REFFYAIVDE ADSILIDEAR TPLIISGPSG KPAEMYYTFA
250 260 270 280 290 300
KIAERLKRDE DYIVEEKEKR VAPTEEGIAK VEKWLNVDHL YEGENQQLVH YLNNAIKAKE
310 320 330 340 350 360
LFHRDRDYVV KDGQVIIVDE FTGRLMFGRR WSDGLHQAVE AKEGVKIEEE TQTLATITFQ
370 380 390 400 410 420
NYFRMYKKLA GMTGTALTEE EEFRKIYGLD VIAIPTNKPM IRIDHPDVVY KTVKAKFKAV
430 440 450 460 470 480
ADDVEERHKR GQPVLVGTVS IEKSEYLSQI LTRRGIPHQV LNAKHHEREA EIVAQAGRFG
490 500 510 520 530 540
AVTIATNMAG RGTDILLGGN PDFAARQRMR AEGYAPELIV AATDIIPSQD PEVQAAREVY
550 560 570 580 590 600
LQYLKEEEAK CAEEAEKVRA VGGLCVIGTE RHEARRIDNQ LRGRAGRQGD PGESRFYVSL
610 620 630 640 650 660
EDDLMRLFGG EMVQNLMNKL GIEDDVPIDS PMVSRAIENA QKKVEARNFD IRKHVLQYDD
670 680 690 700 710 720
VMNTQRELIY KQRRQILEGH DTREVVLDAI AATAQSIVEE GVPEDVYFEE WDPSILVALA
730 740 750 760 770 780
EDNGIPKGAV NVEDLKAAVE GVRREQEGRE KLAKVIEQAA IRAYEEKEAR LGAETMRQLE
790 800 810 820 830 840
RFLLLRTVDE KWMDHLDAMD DLREGVGLRA YGQRDPLIEY KMEAMEMFNN MIRSIQRDMV
850 860 870 880 890 900
RNLFIFEVVR EPQRPRIMIE SGSQGAAPRQ PVRAEGKKVG RNDPCPCGSG KKYKFCCGRA
ANA