Q66KH2

PR
Gene name
ergic3
Protein name
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Names
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:447415
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

71-222 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q66KH2

Entry ID Method Resolution Chain Position Source
AF-Q66KH2-F1 Predicted AlphaFoldDB

No variants for Q66KH2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q66KH2

No associated diseases with Q66KH2

2 regional properties for Q66KH2

Type Name Position InterPro Accession
domain Endoplasmic reticulum vesicle transporter, C-terminal 146 - 369 IPR012936
domain Endoplasmic reticulum vesicle transporter, N-terminal 7 - 96 IPR039542

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein
  • Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
endoplasmic reticulum-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
METLHRLRQF DAYPKTLEDF RVKTCGGAVV TVISGLIMLI LFFSELQYYL TKEVYPELFV
70 80 90 100 110 120
DKSRGDKLKI NIDVIFPHMP CAYLSIDAMD VAGEQQLDVE HNLFKQRLDL DKKPVTSEAD
130 140 150 160 170 180
RHELGKSEEQ VVFDPKTLDP NRCESCYGAE TDDFSCCNSC DDVREAYRRK GWAFKTPDSI
190 200 210 220 230 240
EQCKREGFSQ KMQEQKNEGC QVYGFLEVNK VAGNFHFAPG KSFQQSHVHV HAVEIHDLQS
250 260 270 280 290 300
FGLDNINMTH EIKHLSFGKD YPGLVNPLDG TSIVAMQSSM MFQYFVKIVP TVYVKVDGEV
310 320 330 340 350 360
LRTNQFSVTR HEKMTNGLIG DQGLPGVFVL YELSPMMVKF TEKHRSFTHF LTGVCAIIGG
370 380
VFTVAGLIDS LIYYSTRAIQ KKIELGKAT