Q66IC8

PR
Gene name
dynlt5 (tctex1d1, zgc:101774)
Protein name
Dynein light chain Tctex-type 5
Names
Tctex1 domain-containing protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:447884
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-97 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q66IC8

Entry ID Method Resolution Chain Position Source
AF-Q66IC8-F1 Predicted AlphaFoldDB

No variants for Q66IC8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q66IC8

No associated diseases with Q66IC8

1 regional properties for Q66IC8

Type Name Position InterPro Accession
domain GNAT domain 12 - 153 IPR000182

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic dynein complex Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.

1 GO annotations of molecular function

Name Definition
dynein intermediate chain binding Binding to an intermediate chain of the dynein complex.

2 GO annotations of biological process

Name Definition
cilium assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
microtubule-based movement A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDLAKEKAR LLKKRGSLSS LGSHEVRAIG KTKDSISTLS YMEEHGHHDD IQRPTVQMEN
70 80 90 100 110 120
TYRITPSRRF PVLTVKDLLK DVLTSYLQEE KYETELCRQM TKTITEVVKA RVKDLMIPRY
130 140 150 160 170
KIIVVISIGQ IKDQNIRMGS RCLWDDNHDN FSSHIFKNNS LFAAATVFGV YFE