Q66FR1
Gene name |
coaA |
Protein name |
Pantothenate kinase |
Names |
Pantothenic acid kinase |
Species |
Yersinia pseudotuberculosis serotype I (strain IP32953) |
KEGG Pathway |
yps:YPTB0274 |
EC number |
2.7.1.33: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q66FR1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q66FR1-F1 | Predicted | AlphaFoldDB |
No variants for Q66FR1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q66FR1 | |||||
No associated diseases with Q66FR1
12 regional properties for Q66FR1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Receptor L-domain | 52 - 172 | IPR000494-1 |
| domain | Receptor L-domain | 366 - 484 | IPR000494-2 |
| domain | Protein kinase domain | 720 - 987 | IPR000719 |
| domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | 722 - 975 | IPR001245 |
| domain | Furin-like cysteine-rich domain | 190 - 343 | IPR006211 |
| repeat | Furin-like repeat | 232 - 280 | IPR006212-1 |
| repeat | Furin-like repeat | 501 - 552 | IPR006212-2 |
| repeat | Furin-like repeat | 557 - 607 | IPR006212-3 |
| active_site | Tyrosine-protein kinase, active site | 841 - 853 | IPR008266 |
| binding_site | Protein kinase, ATP binding site | 726 - 753 | IPR017441 |
| domain | Tyrosine-protein kinase, catalytic domain | 720 - 976 | IPR020635 |
| domain | Growth factor receptor domain 4 | 511 - 642 | IPR032778 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.33 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| pantothenate kinase activity | Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| coenzyme A biosynthetic process | The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKREQSLAT | PYLQFDRTQW | AALRDSVPLT | LTEEEIVKLK | GINEDLSLDE | VAQIYLPLSR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLNFYISSNL | RRQAVLEQFL | GTDGQRIPYV | IGIAGSVAVG | KSTTARLLQA | LLSRWPEHRS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VELITTDGFL | HPNKVLNERG | LMKKKGFPES | YDMHNLVKFV | SEVKSGADYV | TAPVYSHLIY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DVVPDGNKVI | KQPDILILEG | LNVLQSGMDY | PHDPHHVFVS | DFVDFSIYVD | APEDLLQSWY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| INRFLKFRQG | AFSNPDSYFH | NYAKLPETEA | IKIATQLWNE | INGLNLKQNI | LPTRERASLI |
| 310 | |||||
| MTKSANHAVE | SVRLRK |