Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q65SK9

Entry ID Method Resolution Chain Position Source
AF-Q65SK9-F1 Predicted AlphaFoldDB

No variants for Q65SK9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q65SK9

No associated diseases with Q65SK9

5 regional properties for Q65SK9

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 320 - 489 IPR000795
domain Small GTP-binding protein domain 323 - 479 IPR005225
domain Translation initiation factor IF-2, N-terminal 245 - 295 IPR006847
domain Translation initiation factor IF- 2, domain 3 596 - 710 IPR023115
domain Translation initiation factor IF-2, domain II 496 - 589 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDKETQNEN APKKLSLQRR VKTTVAGGKV QVEVRKSRKI DTEAAKKAAE EAKLKAQEAA
70 80 90 100 110 120
EKAAAEKAEK EAAEKAKKNA EKARVAAAVK KPEPVKVVDA EKDRIKAEEA ELRRKADELA
130 140 150 160 170 180
RQKAEEQARK AAEEAKRLAE LAADRETTEV SDDFSDYHLT STYAREAEDE EERRKEGRGR
190 200 210 220 230 240
GKNKVGKAKK GGRDDNGSKD ERNADRRNQK DVKGKGKQGK KGSSAIQQAF TKPAQAVNRD
250 260 270 280 290 300
VVIGETITVA ELANKMAVKA TEIIKTMMKM GEMVTINQVI DQETAQLVAE EMGHKVILRK
310 320 330 340 350 360
ENELEESVLE DRDVNAEKVT RAPVVTIMGH VDHGKTSLLD YIRKAKVAAG EAGGITQHIG
370 380 390 400 410 420
AYHVETNGKM ITFLDTPGHA AFTSMRARGA KATDIVVLVV AADDGVMPQT IEAIQHARAA
430 440 450 460 470 480
SVPLVVAVNK IDKPEANPDR VEQELLQYDV VSEKFGGDTQ FVYVSAKKGT GVDELLDAIL
490 500 510 520 530 540
LQSEVLELTA VKEGMATGVV IESYLDKGRG PVATILVQSG TLNRGDILLC GFEYGRVRAM
550 560 570 580 590 600
RDELGKDVES AGPSIPVEVL GLSGVPAAGD EATVVRDEKK AREVALYRQG KFREVKLARQ
610 620 630 640 650 660
QKAKLENMFS NMAEGDVAEL NVIVKADVQG SVEAIVQSLQ ELSTEEVKVK VVGSGVGGIT
670 680 690 700 710 720
ETDATLAAAS NAIIVGFNVR ADASARRIIE TENIDLRYYS IIYELLNEIK AAMSGMLQPE
730 740 750 760 770 780
FKQEIIGLAE VRDVFRSPKF GAIAGCMVTE GVIKRNNPIR VLRDNVVIFE GELESLRRFK
790 800 810
DDVNEVRNGM ECGIGVKNYN DVKVGDQIEV FEVVEIKRSI