Q65JJ7
Gene name |
pyrH |
Protein name |
Uridylate kinase |
Names |
UK, Uridine monophosphate kinase, UMP kinase, UMPK |
Species |
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) |
KEGG Pathway |
bli:BL01242 |
EC number |
2.7.4.22: Phosphotransferases with a phosphate group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q65JJ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q65JJ7-F1 | Predicted | AlphaFoldDB |
No variants for Q65JJ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q65JJ7 | |||||
No associated diseases with Q65JJ7
1 regional properties for Q65JJ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aspartate/glutamate/uridylate kinase | 7 - 217 | IPR001048 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.4.22 | Phosphotransferases with a phosphate group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| UMP kinase activity | Catalysis of the reaction: ATP + UMP = ADP + UDP. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' CTP biosynthetic process | The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKPKYNRIV | LKLSGEALAG | EQGNGINPTV | IQSIAKQVKE | IAELDVEVAV | VVGGGNLWRG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTGSDLGMDR | ATADYMGMLA | TVMNSLALQD | SLETLGIQSR | VQTSIEMRQV | AEPYIRRKAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RHLEKKRVVI | FAAGTGNPYF | STDTTAALRA | AEIEADVILM | AKNNVDGVYN | ADPRTDETAV |
| 190 | 200 | 210 | 220 | 230 | |
| KYEKLSYLDV | LKDGLAVMDS | TASSLCMDND | IPLIVFSIME | EGNIKRAVLG | EQIGTIVRGK |