Q65FN2
Gene name |
tgl |
Protein name |
Protein-glutamine gamma-glutamyltransferase |
Names |
Transglutaminase, TGase |
Species |
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) |
KEGG Pathway |
bli:BL02523 |
EC number |
2.3.2.13: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q65FN2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q65FN2-F1 | Predicted | AlphaFoldDB |
No variants for Q65FN2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q65FN2 | |||||
No associated diseases with Q65FN2
No regional properties for Q65FN2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q65FN2 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.13 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein-glutamine gamma-glutamyltransferase activity | Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sporulation resulting in formation of a cellular spore | The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MISVSGYRLR | PEDIEKLNVS | QTQRDIANRM | LAMPSGYRYG | SISELLFELR | FREHTVKSAR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELINSGAKFA | TFSKTYGNEE | FWRVTPEGAL | ELKYRAPASK | AIRNIFESGP | SYAFECATAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VIIFYMALLK | TIGDQTFDRN | YQRIILYDWH | YERLPIYTDK | GNDYLPGDCL | YFKNPEFDPS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RPQWRGENAI | LLENNLYAAH | GLGILSGETI | IEKLNGLRKP | HAQTSAYLLS | QVTRVDIPAL |
| IQMIR |