Q65EC5

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)
KEGG Pathway
bli:BL03381
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

761-835 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q65EC5

Entry ID Method Resolution Chain Position Source
AF-Q65EC5-F1 Predicted AlphaFoldDB

No variants for Q65EC5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q65EC5

No associated diseases with Q65EC5

9 regional properties for Q65EC5

Type Name Position InterPro Accession
domain Helicase, C-terminal 421 - 575 IPR001650
conserved_site SEC-C motif 821 - 839 IPR004027
domain SecA DEAD-like, N-terminal 5 - 382 IPR011115
domain SecA Wing/Scaffold 568 - 778 IPR011116
domain SecA, preprotein cross-linking domain 226 - 338 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 87 - 257 IPR014001
domain SecA motor DEAD 1 - 570 IPR014018
conserved_site SecA conserved site 480 - 495 IPR020937
domain SecA, C-terminal helicase domain 400 - 540 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGILNKVFD PTKRTLSRYE KKANEIDALK ADIEKLSDEA LKQKTIEFKE RLEKGETVDD
70 80 90 100 110 120
LLVEAFAVVR EASRRVTGMF PFKVQLMGGV ALHEGNIAEM KTGEGKTLTS TMPVYLNALS
130 140 150 160 170 180
GKGVHVVTVN EYLASRDAEE MGKIFEFLGL TVGLNLNSLS KDEKREAYAA DITYSTNNEL
190 200 210 220 230 240
GFDYLRDNMV LYKEQMVQRP LHFAVIDEVD SILIDEARTP LIISGQAAKS TKLYVQANAF
250 260 270 280 290 300
VRTLKADQDY TYDVKTKGVQ LTEEGMTKAE KAFGIENLFD VRHVALNHHI AQALKAHAAM
310 320 330 340 350 360
HKDVDYVVED GQVVIVDSFT GRLMKGRRYS DGLHQAIEAK EGLEIQNESM TLATITFQNY
370 380 390 400 410 420
FRMYEKLAGM TGTAKTEEEE FRNIYNMQVV TIPTNKPIAR DDRPDLIYRT MEGKFKAVAE
430 440 450 460 470 480
DVAQRYMVGQ PVLVGTVAVE TSELISRLLK NKGIPHQVLN AKNHEREAQI IEDAGQKGAV
490 500 510 520 530 540
TIATNMAGRG TDIKLGEGVK ELGGLAVIGT ERHESRRIDN QLRGRSGRQG DPGITQFYLS
550 560 570 580 590 600
MEDELMKRFG AERTMAMLDR FGMDDSTPIQ SKMVSRAVES SQKRVEGNNF DARKQLLQYD
610 620 630 640 650 660
DVLRQQREVI YKQRFEVIDS DNLRSIVENM IKASLERAVA SYTPKEDLPE EWNLDGLVEL
670 680 690 700 710 720
VNANFLDEGG VEKSDIFGKE PEEITELIYD RIKTKYDEKE ERYGSEQMRE FEKVIVLREV
730 740 750 760 770 780
DTKWMDHIDA MDQLRQGIHL RAYAQTNPLR EYQMEGFAMF ENMIAAIEDD VAKFVMKAEI
790 800 810 820 830 840
ENNLEREEVI QGQTTAHQPK EGDEEKQAKK KPVRKAVDIG RNDPCYCGSG KKYKNCCGRT
E