Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

0 structures for Q65143

Entry ID Method Resolution Chain Position Source

No variants for Q65143

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q65143

No associated diseases with Q65143

10 regional properties for Q65143

Type Name Position InterPro Accession
domain Helicase, C-terminal 885 - 1032 IPR001650
domain HRDC domain 1217 - 1297 IPR002121
conserved_site DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site 798 - 807 IPR002464
domain DEAD/DEAH box helicase domain 679 - 846 IPR011545
domain BDHCT 377 - 417 IPR012532
domain Helicase superfamily 1/2, ATP-binding domain 672 - 873 IPR014001
domain RQC domain 1080 - 1200 IPR018982
domain ATP-dependent DNA helicase RecQ, zinc-binding domain 1003 - 1075 IPR032284
domain RecQ-like DNA helicase BLM, N-terminal domain 1 - 372 IPR032437
domain RecQ-like DNA helicase BLM, BDHCT-box associated domain 431 - 655 IPR032439

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MCAGFYVAVH PWLEAQSLHK VGHTGNLAAR LHDGSYTTCF TDEWKYCFTL ETSTKKDAQK
70 80 90 100 110 120
IEAGVLYCAQ FFRVKNKELV CLLPEKIKQL AEDVANCLDI SYTLCDSPTY EMNDSTIVVE
130 140 150 160 170 180
PSLPSDPLIS KEKLRHLVIT PVEDEEHFAD DVLFFSTDET RTAIEDRLYQ KEAANMGYQE
190 200 210 220 230 240
LRRSGRAILQ MACRCGKTRV AYLILSNYLQ GKVLYLVPGL SLLRQTLEKL YQYGISLKNV
250 260 270 280 290 300
LLVGSDQTRI VLNHDNIEMT TNPVFIAKRI REAPSLLVIA TYQSSTLLVD DFDLIISDEC
310 320 330 340 350 360
HRICGEWETR PFTHVLLNFK KGHRLFLTAT PRYDTPLSMK NRELFGGVAF RYYLREGIEA
370 380 390 400 410 420
GYVNDFELQM VAAPKLAHQP SNREETTKQI IVKQIIMALA YLKTNIPAPK MLVFTRDIKQ
430 440 450 460 470 480
ARELYAELVD QGVYALIAHS TLPRQVILKT FTEFCSSKEP VILLNCRLFQ EGVEVPELNA
490 500 510 520 530 540
VFFAAPRHSP RDIIQSICRP LNKQVQKPHA TIFLPLEVNT ENVCLDRFSS IIPFADALAS
550 560 570 580 590 600
EDPRFYEHLL NPSEVAYPIN WIGAHGSVSE LLQLARHAIR YGTQGKIDRL TRSERLPWKA
610 620 630 640 650 660
AFAELKRTVE ICCRYPKIND GFHFGGATLR FDTWYKWVIK SYLQYKNKEP SSLEPYQVSD
670 680 690 700 710 720
LESLQDWTTR GVGGPYPWEE SMAFLETWLA QNKGELVAID IHQGGWIGLD ATPMERLSGV
730 740 750 760 770 780
LTTVSQRDGR SYGKNKKLRP KKGFMIPPQQ AEDLDRIFGK HNLKWRKDRV NGFLKEDEHG
790 800 810 820 830 840
NYTGEPTCIQ EAYRTFKEYV KTNPEYIEKY WPGYAKGKHK HQELPHIWES GLAPPRYKAF
850
KDGNKQLIQR SPKKKDIKN