Q64N73

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Bacteroides fragilis (strain YCH46)
KEGG Pathway
bfr:BF4326
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

47-118 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q64N73

Entry ID Method Resolution Chain Position Source
AF-Q64N73-F1 Predicted AlphaFoldDB

No variants for Q64N73

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q64N73

No associated diseases with Q64N73

9 regional properties for Q64N73

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 14 - 145 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 327 - 457 IPR001247-2
domain S1 domain 626 - 699 IPR003029
domain K Homology domain 556 - 624 IPR004087
domain K Homology domain, type 1 560 - 620 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 148 - 212 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 462 - 533 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 260 - 324 IPR015848
domain RNA-binding domain, S1 627 - 699 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MINPIVKTIE LGDGRTITLE TGKLAKQADG SVMLRMGNTM LLATVCAAKD AVPGTDFMPL
70 80 90 100 110 120
QVEYKEKFAA FGRFPGGFTK REGRASDYEI LTCRLVDRAL RPLFPDNYHA EVYVNIILFS
130 140 150 160 170 180
ADGVDMPDAL AGLAASAALA VSDIPFNGPI SEVRVARIDG KFVINPTFDQ LEQADMDIMV
190 200 210 220 230 240
AATYENIMMV EGEMSEVSEA ELLEAMKVAH EAIKVHCKAQ MELTEMVGKT VKREYCHEEN
250 260 270 280 290 300
DEELRKAVHD ACYDKSYAIA ASGNRNKHER QDAFDAIRDE FKAQFSEEEL EEKGALIDRY
310 320 330 340 350 360
YHDVEKEAMR RCILDEGKRL DGRKTTEIRP IWCEVGYLPG PHGSAIFTRG ETQSLTSVTL
370 380 390 400 410 420
GTKLDEKIID DVLAHGKERF LLHYNFPPFS TGEAKAQRGV GRREIGHGNL AHRALKRMIP
430 440 450 460 470 480
EDYPYVVRVV SDILESNGSS SMATVCAGTL ALMDAGVKIK KPVSGIAMGL IKNAGEEKYA
490 500 510 520 530 540
VLSDILGDED HLGDMDFKVT GTKDGITATQ MDIKVDGLSY EILERALNQA KEGRMHILGK
550 560 570 580 590 600
IEETISEPRT ELKDHAPRIE TMTIPKEFIG AVIGPGGKII QGMQEETGAT ITIEEIDNVG
610 620 630 640 650 660
RIEISGTNKK SIDDAIRLIK GIVAVPEVGE VYKGKVRSIM PYGAFVEFLP GKDGLLHISE
670 680 690 700
IDWKRLETVE EAGIKEGDEI EVKLIDIDPK TGKFKLSRKV LLPRPEKK