Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q640U3

Entry ID Method Resolution Chain Position Source
AF-Q640U3-F1 Predicted AlphaFoldDB

No variants for Q640U3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q640U3

No associated diseases with Q640U3

8 regional properties for Q640U3

Type Name Position InterPro Accession
domain Immunoglobulin subtype 2 26 - 116 IPR003598-1
domain Immunoglobulin subtype 2 142 - 211 IPR003598-2
domain Immunoglobulin subtype 20 - 127 IPR003599-1
domain Immunoglobulin subtype 136 - 222 IPR003599-2
domain Immunoglobulin-like domain 29 - 123 IPR007110-1
domain Immunoglobulin-like domain 130 - 220 IPR007110-2
domain Immunoglobulin V-set domain 21 - 119 IPR013106-1
domain Immunoglobulin V-set domain 146 - 206 IPR013106-2

Functions

Description
EC Number
Subcellular Localization
  • Cell junction, tight junction
  • Cell membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
bicellular tight junction An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
cytoplasmic microtubule Any microtubule in the cytoplasm of a cell.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHTLIRSFLG LWYVLGALAQ TEIKLVADEN VTLPCRHSLG HLGIQSLDIE WLSNISDHGK
70 80 90 100 110 120
QVLLSYSGGQ VYNAENHKGR YSFVSKYLEG DASLFIRSLQ PSDAGQYICK VKNAGQYQWS
130 140 150 160 170 180
FITVIVLVKP SELACSSEGA QLEGKNVTLN CKSTAGTKPL NYRWVRVNLK DNVERPVQST
190 200 210 220 230 240
ARIGPENQLL LHNLSKTDNG SYRCEVSNEV GKRTCDVDVT VQSVSNTGIL AGVACGVVVG
250 260 270 280 290 300
VFLIFFTVWL LFHKKEFKKR EEEEFFNEIR EDAEAPKARL VKPGSSSSDS RSSQSGSSST
310 320 330
RSTTNSASRS QRTHSTQETP HGEQRHHCLE KI