Q640K6
Gene name |
dpysl3-b (crmp4) |
Protein name |
Dihydropyrimidinase-related protein 3-B |
Names |
DRP-3-B, Collapsin response mediator protein 4, CRMP-4, xCRMP4 |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:494650 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q640K6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q640K6-F1 | Predicted | AlphaFoldDB |
No variants for Q640K6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q640K6 | |||||
No associated diseases with Q640K6
5 regional properties for Q640K6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | MmeI-like, DNA-methyltransferase domain | 322 - 579 | IPR046816 |
| domain | MmeI-like, N-terminal domain | 8 - 158 | IPR046817 |
| domain | MmeI-like, C-terminal domain | 803 - 878 | IPR046818 |
| domain | MmeI-like, helicase spacer domain | 169 - 316 | IPR046819 |
| domain | MmeI-like, target recognition domain | 596 - 800 | IPR046820 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| growth cone | The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament bundle assembly | The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. |
| positive regulation of filopodium assembly | Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone. |
| regulation of cell migration | Any process that modulates the frequency, rate or extent of cell migration. |
| regulation of neuron projection development | Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). |
| response to axon injury | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYQGKKNIP | RITSDRLLIK | GGRIVNDDQS | FYADIYMEDG | LIKQIGDNLI | VPGGVKTIEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NGKMVIPGGI | DVHTHLQMPY | RGMTTVDDFF | QGTKAALAGG | TTMIVDHVIP | EPEASLTEAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EKWREWADGK | TCCDYSLHVD | ITHWSDSVKQ | EVETLVKQKG | VNSFMVYMAY | KDMYQMSNTE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYEIFTFLGG | LGAIAQVHAE | NGDIIAQEQN | RMLELGITGP | EGHVLSRPEE | LEAEAVFRAI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TIASQTNCPL | YVTKVMSKSS | VDLISQARKK | GYVVFGEPIT | ASLGTDGTHY | WSKNWAKAAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FVTSPPLSPD | PTTPDYINSL | LASGDLQVTG | SAHATFSTAQ | KAIGKDNFTL | IPEGTNGIEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RMSVIWDKSV | ATGKMDENQF | VAVTSTNAAK | IFNLYPRKGR | IAVGSDSDLV | IWDPDAVKIV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SAKSHHSAAE | YNIFEGMELR | GAPLVVICQG | KIMMEDGTLH | ATQGTGRFIP | CSPFPDYVYK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RIKARTKMAE | LHAVPRGMYD | GPVHDLASTP | KAGTPAGSTK | GSPTKQTAPV | RNLHHSGFSL |
| 550 | 560 | 570 | |||
| IGNQADESGV | RSASRRIVAP | PGGRSNITSL | S |