Q63W75

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Burkholderia pseudomallei (strain K96243)
KEGG Pathway
bps:BPSL1013
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q63W75

Entry ID Method Resolution Chain Position Source
AF-Q63W75-F1 Predicted AlphaFoldDB

No variants for Q63W75

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q63W75

No associated diseases with Q63W75

2 regional properties for Q63W75

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 200 - 211 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 637 - 649 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKSSGSARAT RRNAVSSSSA PAHAEPPARR AAKPARKLDG AAARPLAPTN AASAKPQGRT
70 80 90 100 110 120
REDKDRPLFE DIRYLGRLLG DVVREQEGDA VFDVVETIRQ TAVKFRREDD KAAAQTLEKM
130 140 150 160 170 180
LRKLTPEQTV SVVRAFSYFS HLANIAEDRH HNRRRRIHAL AGSAAQAGTV AYALDKLKQA
190 200 210 220 230 240
GDASSKTIKQ FFEGALIVPV LTAHPTEVQR KSILDAQHDI ARLLAERDQP LTARELAHNE
250 260 270 280 290 300
ALLRARVTTL WQTRMLRDAR LTVADEIENA LSYYRATFLD ELPALYADIE EALAEHGLRA
310 320 330 340 350 360
RVPAFFQMGS WIGGDRDGNP NVTAATLDEA ISRQAAVIFE HYLEQVHKLG AELSVSNLLV
370 380 390 400 410 420
GASDALKALA AASPDQSPHR VDEPYRRALI GVYTRLAASA RVRLGEGTVP VRSAGRGAAP
430 440 450 460 470 480
VRATPYADAE EFAADLRVLT DSLALHHGES LATPRLAPLM RAAEVFGFHL ASIDLRQSSD
490 500 510 520 530 540
IHEAVVAELL ARGGVEADYA ALPEADKLRV LLAALADPRP LRSPYLDYSD LAKSELGVLE
550 560 570 580 590 600
RAHAIRAQFG ARAVRNYIIS HTETVSDLVE VLLLQKETGL FEGTLGTPHA NARNGLMVIP
610 620 630 640 650 660
LFETIADLRN ASDIMRAFFA LPGVGELLAH QGHEQEVMLG YSDSNKDGGF LTSNWELYRA
670 680 690 700 710 720
ELALVDLFDE RGIKLRLFHG RGGTVGRGGG PTYQAILSQP PGTVNGQIRL TEQGEVIASK
730 740 750 760 770 780
FANPEIGRRN LETVVAATLE ATLAPHSNAP KQLPAFEAAM QTLSDAAMAS YRALVYETPG
790 800 810 820 830 840
FTDYFFSSTP ITEIAELNIG SRPASRKLQD PKNRKIEDLR AIPWGFSWGQ CRLLLTGWYG
850 860 870 880 890 900
FGSAVAAYLD GAPDAAERGK RVALLKKMNK TWPFFANLLS NMDMVLAKTD LAVASRYAQL
910 920 930 940 950 960
VADKKLRKHV FERIVAEWHR TADALAEITG AHARLAANPL LARSIKNRFP YLDPLNHLQV
970 980 990
ELIKRHRAGD TNARLRRGIH LTINGIAAGL RNTG