Q62HU9

PR
Gene name
ubiD
Protein name
3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Names
Polyprenyl p-hydroxybenzoate decarboxylase
Species
Burkholderia mallei (strain ATCC 23344)
KEGG Pathway
bma:BMA2151
EC number
4.1.1.98: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

264-333 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q62HU9

Entry ID Method Resolution Chain Position Source
AF-Q62HU9-F1 Predicted AlphaFoldDB

No variants for Q62HU9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q62HU9

No associated diseases with Q62HU9

3 regional properties for Q62HU9

Type Name Position InterPro Accession
domain Lactate/malate dehydrogenase, N-terminal 23 - 161 IPR001236
active_site L-lactate dehydrogenase, active site 191 - 197 IPR018177
domain Lactate/malate dehydrogenase, C-terminal 165 - 325 IPR022383

Functions

Description
EC Number 4.1.1.98 Carboxy-lyases
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKYRDLRDFI HGLEQRGELR RVTQPVSPVL EMTELCDRVL RAGGPALLFD APAGHRFPVL
70 80 90 100 110 120
GNLFGTPRRV ALGMGVDADD EAALASLRDI GRLLSALKEP DPPKRLKDAG KLLSLAKAVW
130 140 150 160 170 180
DMGPKTVSAP PCQEIVWEGD DVDLHKLPIQ TCWPGDAGPL LTWGLTVTRG PNKTRQNLGI
190 200 210 220 230 240
YRQQLIGRNK LIMRWLAHRG GALDFREFAL KHPGQPYPVA VVLGADPATM LGAVTPVPDS
250 260 270 280 290 300
LSEYQFAGLL RGARTELAKC VTPGVDALQV PARAEIVLEG FIHPQQGAPA PAPEGAPPRP
310 320 330 340 350 360
AAGAAAGYEH ALEGPYGDHT GYYNEQEWFP VFTVERITMR RDAIYHSTYT GKPPDEPAVL
370 380 390 400 410 420
GVALNEVFVP LLQKQFAEIT DFYLPPEGCS YRMAIVQMKK SYAGHAKRVM FGVWSFLRQF
430 440 450 460 470 480
MYTKFIVVVD EDVNVRDWKE VIWAITTRVD PARDTVLVEN TPIDYLDFAS PVAGLGSKMG
490 500 510
LDATNKWPGE TQREWGRPIE MDAAVKARVD RLWTEIGLS