Q61J97

PR
Gene name
mett-10
Protein name
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
Names
N6-adenosine-methyltransferase mett-10
Species
Caenorhabditis briggsae
KEGG Pathway
cbr:CBG_09879
EC number
2.1.1.346: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q61J97

Entry ID Method Resolution Chain Position Source
AF-Q61J97-F1 Predicted AlphaFoldDB

No variants for Q61J97

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q61J97

No associated diseases with Q61J97

No regional properties for Q61J97

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q61J97

Functions

Description
EC Number 2.1.1.346 Methyltransferases
Subcellular Localization
  • Nucleus
  • Accumulates in nuclei as cells enter meiosis
  • During meiotic prophase, expression is predominantly nuclear, but does not co-localize with DNA
  • Recruited to the nucleus by dlc-1, a component of the dynein complex
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
23S rRNA (adenine(1618)-N(6))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.

3 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
meiotic cell cycle Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQGNEMHPR NPYRDKPPDF KALAIEYPEF RKFCQYVSNG KVTLDFRKDA AVRCLTQTLL
70 80 90 100 110 120
KKDFSLNVNL PAGHLVPRVP QKLNYCLLID DILQANSITS NVVGIDIGTG TSCIHALIGA
130 140 150 160 170 180
RHFGWKFVAT DGDENSVQVA HENVARNEMG DSICVVHVNP AVKTVLMDVI NSMPDSEFSF
190 200 210 220 230 240
CMCNPPFFEK SDKEERFCEE PSLSNETYSN NFDFDMRSAP HSETIASSAE LYVEGGEVAF
250 260 270 280 290 300
VNRIIDDSVC LRDRIKFYTT MIGRKSSLKP LLQRLERFGE NVKFLVHPLN QGKTKRWMLA
310 320 330 340 350 360
WTFAKEMTLN TALKNSSISF QCPKPGLVKL MQEISRLGGR WSQEQPSVLV AEFKSVTWTN
370 380 390 400 410 420
QRARRKANAL LFENSAKRAR WNTSSVACEA MMGNGDGKDS YTNSGNFVYS ESFKTSDPAA
430 440 450 460 470 480
VETSSQAYFP LPSGVTPRPI VKLRIQVDPD DKCDTLSFEL ISGAKQHLHQ IVQYLKNLLC
R