| activation of cysteine-type endopeptidase activity |
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. |
| activation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process. |
| ADP metabolic process |
The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate. |
| apoptotic process |
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| apoptotic signaling pathway |
The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. |
| ATP metabolic process |
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. |
| cellular response to chromate |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus. |
| cellular response to hypoxia |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. |
| cellular response to lipid |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. |
| cellular response to mechanical stimulus |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. |
| cellular response to nicotine |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus. |
| cellular response to organic substance |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. |
| cerebral cortex development |
The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. |
| cytokine-mediated signaling pathway |
The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. |
| epithelial cell proliferation |
The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. |
| extrinsic apoptotic signaling pathway |
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered. |
| extrinsic apoptotic signaling pathway in absence of ligand |
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered. |
| extrinsic apoptotic signaling pathway via death domain receptors |
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered. |
| glucose catabolic process |
The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. |
| glucose homeostasis |
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. |
| intrinsic apoptotic signaling pathway |
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP). |
| intrinsic apoptotic signaling pathway in response to DNA damage |
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. |
| pore complex assembly |
The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases. |
| positive regulation of apoptotic process |
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
| positive regulation of apoptotic process by virus |
Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
| positive regulation of B cell differentiation |
Any process that activates or increases the frequency, rate or extent of B cell differentiation. |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process. |
| positive regulation of epithelial cell proliferation |
Any process that activates or increases the rate or extent of epithelial cell proliferation. |
| positive regulation of glucokinase activity |
Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. |
| positive regulation of granulosa cell apoptotic process |
Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process. |
| positive regulation of insulin secretion |
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus |
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. |
| positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress |
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress. |
| positive regulation of mitochondrial membrane potential |
Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. |
| positive regulation of neuron death |
Any process that activates or increases the frequency, rate or extent of neuron death. |
| positive regulation of proteolysis |
Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. |
| positive regulation of release of cytochrome c from mitochondria |
Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. |
| positive regulation of T cell differentiation |
Any process that activates or increases the frequency, rate or extent of T cell differentiation. |
| positive regulation of type B pancreatic cell development |
Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. |
| regulation of apoptotic process |
Any process that modulates the occurrence or rate of cell death by apoptotic process. |
| regulation of cysteine-type endopeptidase activity involved in apoptotic process |
Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis. |
| regulation of mitochondrial membrane permeability |
Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane. |
| release of cytochrome c from mitochondria |
The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation. |
| response to amino acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. |
| response to benzene |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus. |
| response to calcium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. |
| response to estradiol |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. |
| response to ethanol |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus. |
| response to glucocorticoid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. |
| response to glucose |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. |
| response to hydrogen peroxide |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. |
| response to oleic acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus. |
| response to progesterone |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. |
| response to testosterone |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus. |
| response to xenobiotic stimulus |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. |
| spermatogenesis |
The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. |
| suppression by virus of host apoptotic process |
Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication. |
| type B pancreatic cell proliferation |
The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. |
