Q60NC0

PR
Gene name
mec-10
Protein name
Degenerin mec-10
Names
Mechanosensory abnormality protein 10
Species
Caenorhabditis briggsae
KEGG Pathway
cbr:CBG_22775
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

187-286 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q60NC0

Entry ID Method Resolution Chain Position Source
AF-Q60NC0-F1 Predicted AlphaFoldDB

No variants for Q60NC0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q60NC0

No associated diseases with Q60NC0

1 regional properties for Q60NC0

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 2 - 390 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell body membrane The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
ligand-gated sodium channel activity Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.

5 GO annotations of biological process

Name Definition
detection of mechanical stimulus involved in sensory perception of touch The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
mechanosensory behavior Behavior that is dependent upon the sensation of a mechanical stimulus.
positive regulation of detection of mechanical stimulus involved in sensory perception of touch Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
positive regulation of mechanosensory behavior Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.
sodium ion transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRGPPNPRM FKFQPNPKVK NRFQDEADLR SLRSFKTDFS NYLASDTNFL NVAEIMTSYA
70 80 90 100 110 120
YGESNNANEK EIQCDLLTEN GGIEIDPTRL SYRERIRWHL QQFCYKTSSH GIPMLGQAPN
130 140 150 160 170 180
SLYRAVWVFL LLICAIQFIN QAVAVIQKYQ KMDKITDIQL KFDTAPFPAI TLCNLNPYKD
190 200 210 220 230 240
SVIRSHDSIS KILGVFKSVM KKAGDSSAEA SDDGVEYDMD GITIQAKRRK RGAGEKGTFE
250 260 270 280 290 300
PANSACECDE EDGSNECEEK STEKPSSDND MCICAFDRQT NDAWPCHRRE QWTNTTCQAC
310 320 330 340 350 360
DEHYLCSKKA KKGTKRSEIK KEPCICESKG LFCIKHEHAA LVLNLWEYFG DTEEFSDIST
370 380 390 400 410 420
EEREALGFGN MTDEVAIVTK AKENIIFAMS ASEEQRILMS QAKHNLIHKC SFNGKPCDID
430 440 450 460 470 480
KDFELVADPT FGNCFVFNHD REIFKSSVRA GPQYGLRVML FVNASDYLPT SEAVGIRLTI
490 500 510 520 530 540
HDKDDFPFPD TFGYSAPTGY ISSFGMRMKK MSRLPAPYGD CVEDGTTSNY IYKGYAYSTE
550 560 570 580 590 600
GCYRTCFQEL IIDRCGCSDP RFPSIGGVQP CQVFNKNHRE CLEKHTHQIG EIHGSFKCRC
610 620 630 640 650 660
QQPCNQTIYT TSYSEAIWPS QALNISLGHC EKEAEECNEE YKENAAMLEV FYEALNFEVL
670 680 690 700 710 720
AESEAYGIVK MMADFGGHLG LWSGVSVMTC CEFVCLVLEL LYMAVTHHIT QERIRRRENA
ANEF