Q60K16
Gene name |
CBG24265 |
Protein name |
Probable tRNA (uracil-O(2)-)-methyltransferase |
Names |
|
Species |
Caenorhabditis briggsae |
KEGG Pathway |
cbr:CBG_24265 |
EC number |
2.1.1.211: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q60K16
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q60K16-F1 | Predicted | AlphaFoldDB |
No variants for Q60K16
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q60K16 | |||||
No associated diseases with Q60K16
10 regional properties for Q60K16
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA recognition motif domain | 2 - 75 | IPR000504-1 |
| domain | RNA recognition motif domain | 81 - 156 | IPR000504-2 |
| domain | K Homology domain | 194 - 265 | IPR004087-1 |
| domain | K Homology domain | 275 - 348 | IPR004087-2 |
| domain | K Homology domain | 404 - 475 | IPR004087-3 |
| domain | K Homology domain | 486 - 558 | IPR004087-4 |
| domain | K Homology domain, type 1 | 198 - 261 | IPR004088-1 |
| domain | K Homology domain, type 1 | 280 - 344 | IPR004088-2 |
| domain | K Homology domain, type 1 | 408 - 471 | IPR004088-3 |
| domain | K Homology domain, type 1 | 491 - 555 | IPR004088-4 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.211 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| tRNA (uracil) methyltransferase activity | Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule. |
| tRNA (uracil-2'-O-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA methylation | The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSPWRCIAEQ | LVEYEEPVDA | KAYFDKIICL | WKEYPNAISN | RINTSVPVEE | ESQVWNEVIA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NFESKYRFDP | ANSSELSIFK | LIQRDYKRQS | FSNNCYEVAF | YEEELLVRFY | PIVLDGQQHP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HFESPYSIAC | KIPSNSSILL | QFFKPVDTPD | DHFEFLKTLA | FKQLVTWLKS | IDLSKTTRKT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HSLLDKESYI | STYRHIREDL | GRPLVEGWTE | NSKPQKVIFE | DCGIASYIQE | LITSGILPKP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RKFVDIGCGN | GLLVHLLNKI | GIPGYGVDVR | SRKVWKTTLS | HVDLRESPVD | PQIVVENRPH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FDADVDLLIG | NHSDELTPWI | PVMAAKLNCN | FFLIPCCPYN | FFGKYLNNGS | HLGPKRMTSQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YESFFEWTVS | VSERLGFDTK | MDRLAIPSTK | RLCIIGRVPE | KGLCPSLEQT | IEHMTQGQKF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VARPREIRNN | NCMHISVTDR | ERIAKKLFDF | ILNASDDVRD | GWRCGGEVPL | AQLAGQLTDD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DKKLMKDQDG | GLQTFLRNHH | QIFHVFQATA | RLRDFRQPVV | SRRQQTNPKK | QEATNRPKQP |
| 550 | 560 | ||||
| CWMSLNHPDG | CPLGPESCRY | LH |