Q60B78

PR
Gene name
surA
Protein name
Chaperone SurA
Names
Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA
Species
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
KEGG Pathway
mca:MCA0602
EC number
5.2.1.8: Cis-trans isomerases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

23-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q60B78

Entry ID Method Resolution Chain Position Source
AF-Q60B78-F1 Predicted AlphaFoldDB

No variants for Q60B78

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q60B78

No associated diseases with Q60B78

7 regional properties for Q60B78

Type Name Position InterPro Accession
domain Dynamin stalk domain 238 - 522 IPR000375
domain Dynamin, GTPase domain 1 - 315 IPR001401
domain Dynamin GTPase effector 658 - 749 IPR003130
conserved_site Dynamin, GTPase region, conserved site 51 - 60 IPR019762
domain GTPase effector domain 663 - 754 IPR020850
domain Dynamin-type guanine nucleotide-binding (G) domain 22 - 315 IPR030381
domain Dynamin, N-terminal 28 - 229 IPR045063

Functions

Description
EC Number 5.2.1.8 Cis-trans isomerases
Subcellular Localization
  • Periplasm
  • Is capable of associating with the outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.

3 GO annotations of molecular function

Name Definition
peptide binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.
peptidyl-prolyl cis-trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
Gram-negative-bacterium-type cell outer membrane assembly The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
protein stabilization Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKISSFRKGR WLGALALFAV VCWSMADAAV DRIVAVVDDG VILESELVRK VDEIKRSLRA
70 80 90 100 110 120
SRASLPPDSV LVRQVLERMI VDKIQIQMAE KMGIQVDDDT LRMAVSQIAQ RNNLTPDQFR
130 140 150 160 170 180
RSLAREGIDY GDFLDQVRSE IAMGRLRASQ INNQIKISDR EVEHYLEAQG GSGAVADREY
190 200 210 220 230 240
RLGHILIATP REASPDEVKK ARERADRVVK ELKAGLDFKD ASIRYSDDPQ ALEGGDLGWR
250 260 270 280 290 300
KLSEIPSHIA EVVGGMKDGE VSDPIRSPGG YHIVKMLAMR GVGEAKLTKT HVRHILIRPN
310 320 330 340 350 360
EVLSDEDAKN KLLALKTRIE NGDDFAELAR GHSDDKGSAI KGGDLGWVKP GALVPPFEEA
370 380 390 400 410 420
MNALDENQLS DPVQTQFGWH LIQVLERQES SDTNEVLKNR ARDELFKRKV DEETELWLRK
430 440 450
IRDEAYVEIR LDETPASPGE DAPAGEDSPE TFMR