Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q609C0

Entry ID Method Resolution Chain Position Source
AF-Q609C0-F1 Predicted AlphaFoldDB

No variants for Q609C0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q609C0

No associated diseases with Q609C0

6 regional properties for Q609C0

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 369 - 538 IPR000795
domain Small GTP-binding protein domain 372 - 528 IPR005225
domain Translation initiation factor IF-2, N-terminal 292 - 342 IPR006847
domain Initiation factor 2 associated domain, bacterial 64 - 103 IPR013575
domain Translation initiation factor IF- 2, domain 3 645 - 759 IPR023115
domain Translation initiation factor IF-2, domain II 544 - 639 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDVTVRQLA GIVGIPLDRL LHQLGDAGLQ ISDADDVLSD AEKMKLLNHL RQSHGKVQES
70 80 90 100 110 120
VTEPKRVTLQ RRSVTELKQG TVPGKGAKTI SVEVRKKRTY VKRSELPETS DRLSEAEQAR
130 140 150 160 170 180
RALEEQQQRE LAEQEARRQQ EEMLREQAAE EERRRQEEAA RTAEERRRRD EEERQAAAER
190 200 210 220 230 240
ETVAAKPAPV AAPPIPRPAP EPRPPARPSA GKPKAEAPRA HPAERETEAR GDKRSAGLSR
250 260 270 280 290 300
KDEYRELQGD DFRKGGGKRK KPKTGRPMLM PEQKHGFEKP TAPIVYEVAV PESITVSDLA
310 320 330 340 350 360
QRMSVKGVEV IKALMKMGVM ATINQVLDQE TAILVVEEMG HKAIAQKEDD LEAEIMANLA
370 380 390 400 410 420
AEAEAPQLPR PPVVTIMGHV DHGKTSLLDY IRKSRVAAGE AGGITQHIGA YQVKTDHGSI
430 440 450 460 470 480
TFLDTPGHAA FTAMRARGAK VTDIVVLVVA ADDGVMPQTR EAVEHSRAAG VPLVVAMNKM
490 500 510 520 530 540
DKADADPDRV KQELVGLNVV PEEWGGDVQF VPVSAKTGAG IDTLLDAILV QAEVLELKAP
550 560 570 580 590 600
VAIPAAGVVL ESKLEKGRGP VADILIQRGT LKKGDFLLCG KEIGRVRAMF NENGKPLKEA
610 620 630 640 650 660
GPSAPIEVLG LSGAPEAGDE FIVVADERKA REIALHREEK LRSTKLAAQQ AAKLEDVFSL
670 680 690 700 710 720
MGSEETIDLN LVIKADVQGS LEALRSALTE LSTDKVKVRV IGGGVGGISE TDANLALASN
730 740 750 760 770 780
AILIGFNVRA DGSARKLIEE RGIDLHYYSV IYNAIDEVKK SINGMLEPEF KEQIIGIAQV
790 800 810 820 830 840
REVFRSSKFG TVAGCLVVEG HVRRNLPIRV LRDNVVIFEG QLESLRRFKD DVNEVKSGME
850 860
CGIAVRNYND VREGDQIEVF EKVQVAPH