Q606M6
Gene name |
prfC |
Protein name |
Peptide chain release factor 3 |
Names |
RF-3 |
Species |
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) |
KEGG Pathway |
mca:MCA1990 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q606M6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q606M6-F1 | Predicted | AlphaFoldDB |
No variants for Q606M6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q606M6 | |||||
No associated diseases with Q606M6
5 regional properties for Q606M6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 9 - 277 | IPR000795 |
| domain | Small GTP-binding protein domain | 14 - 160 | IPR005225 |
| conserved_site | Tr-type G domain, conserved site | 56 - 71 | IPR031157 |
| domain | Peptide chain release factor 3, C-terminal | 384 - 511 | IPR032090 |
| domain | Peptide chain release factor 3, GTP-binding domain | 10 - 276 | IPR041732 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation release factor activity, codon specific | A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of translational termination | Any process that modulates the frequency, rate or extent of translational termination. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSELEFEIER | RRTFAIISHP | DAGKTTLTEK | LLLFGGAIQL | AGSVKGRKAT | RHATSDWMEM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EKQRGISVTT | SVMQFQHRDR | IFNLLDTPGH | EDFSEDTYRT | LTAVDSALMV | IDSAKGVEER |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TIKLMEVCRL | RDTPILTFIN | KLDREGREPV | ELLDEVERVL | NIQCAPITWP | IGMGKRFKGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YHLYEDAIHL | FSASHGDRIV | KGEVVEGLNS | PKLDELLGDI | ADELRMEIEL | VRGASHEFDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DAYRAGRQTP | VFFGSAINNF | GILELLDAFA | EYAPPPQARQ | ARERLVAPGE | DKFSGFVFKI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QANMDPAHRD | RIAFLRVCSG | RYTKGVRLFH | VRSGKAMQVA | NAITFQADSR | ENVEEAYPGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IIGLHNHGTI | QVGDTFTQGE | NLKFEGIPSF | APELFRRVVL | KDPLRSKALQ | RGLQQLSEEG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ATQLFKPLRN | NDLILGAVGV | LQFDVTAFRL | KAEYNVDCVY | EAVPVTTARW | VSCSDPKKLE |
| 490 | 500 | 510 | 520 | ||
| EFKRKVHDNL | AEDGSGYLVY | LATSRVNLSL | TEERWPEIRF | SATREL |