Q605N1

PR
Gene name
proB
Protein name
Glutamate 5-kinase
Names
Gamma-glutamyl kinase, GK
Species
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
KEGG Pathway
mca:MCA2249
EC number
2.7.2.11: Phosphotransferases with a carboxy group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

160-261 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q605N1

Entry ID Method Resolution Chain Position Source
AF-Q605N1-F1 Predicted AlphaFoldDB

No variants for Q605N1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q605N1

No associated diseases with Q605N1

4 regional properties for Q605N1

Type Name Position InterPro Accession
domain Aspartate/glutamate/uridylate kinase 12 - 240 IPR001048
domain PUA domain 283 - 366 IPR002478
conserved_site Glutamate 5-kinase, conserved site 213 - 230 IPR019797
domain Glutamate-5-kinase domain 12 - 262 IPR041739

Functions

Description
EC Number 2.7.2.11 Phosphotransferases with a carboxy group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glutamate 5-kinase activity Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+).
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
L-proline biosynthetic process The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQSRNELPGS RRVIVKIGSA LLTAGGKGLD QPAIGQWVQQ IAELRQQGIQ VVLVSSGSVA
70 80 90 100 110 120
EGMSRLGWKT RPHRLNELQA AASVGQMGLV QTYESLFKRH GLQTAQILLT HDDLSNRERY
130 140 150 160 170 180
LNSRSTILTL LELGVIPVIN ENDTVTTEEI RFGDNDTLGA LVANAVEADL LIILTDQAGL
190 200 210 220 230 240
FERNPSLDPS APLVPQAGIN DPRLNDMVGD SLSGLGRGGM ITKLRAARLA ARSGTATVIA
250 260 270 280 290 300
SGRESGVLPR ILDGEELGTL LIPDVSPLIA RKRWMAGQLK LKGCFVVDEG AARVLRDAGK
310 320 330 340 350 360
SLLPIGVIAV EGEFRRGDLV ACTDSAGQEI ARGLTNYSAE EARLIMRQPS TRIEEILGYV
370
DEPELIHRDN LVLS