Q604W4

PR
Gene name
lpxC
Protein name
UDP-3-O-acyl-N-acetylglucosamine deacetylase
Names
UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase
Species
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
KEGG Pathway
mca:MCA2422
EC number
3.5.1.108: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q604W4

Entry ID Method Resolution Chain Position Source
AF-Q604W4-F1 Predicted AlphaFoldDB

No variants for Q604W4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q604W4

No associated diseases with Q604W4

No regional properties for Q604W4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q604W4

Functions

Description
EC Number 3.5.1.108 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.
UDP-3-O-acyl-N-acetylglucosamine deacetylase activity Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate.

1 GO annotations of biological process

Name Definition
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIKQRTLKNV IRATGVGLHT GEKVYLTLRP AAPNSGIKFR RVDLAEPVVI DARPDNVGDT
70 80 90 100 110 120
TLSTTLVKGD VRISTVEHLL SAFAGLGIDN AYVDVSAPEV PIMDGSAGPF VFLIQSAGVQ
130 140 150 160 170 180
EQEAPKQFIR IKRPLQVEDG DKWARFEPHD GFKVTFTIDF DHPVFDKNSQ TASIEFSSTS
190 200 210 220 230 240
FVKEIARART FGFMRDIEML RKNRLALGGS MDNAIVVDKF RVLNEDGLRS GDEFVKHKIL
250 260 270 280 290 300
DAIGDLYLLG HSLIGSFTGY KSGHGLNNHL LCELLKARDA WEMVSFEDEG YAPISYMRTA
PAGR