Q60184

PR
Gene name
atpC (ahaC, MM_0782)
Protein name
V-type ATP synthase subunit C
Names
V-ATPase subunit C
Species
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
KEGG Pathway
mma:MM_0782
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q60184

Entry ID Method Resolution Chain Position Source
AF-Q60184-F1 Predicted AlphaFoldDB

No variants for Q60184

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q60184

No associated diseases with Q60184

2 regional properties for Q60184

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 127 - 319 IPR000194
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 9 - 71 IPR004100

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
proton-transporting V-type ATPase, V0 domain A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
proton-transporting ATPase activity, rotational mechanism Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.

1 GO annotations of biological process

Name Definition
proton motive force-driven plasma membrane ATP synthesis The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLLENLWGK KPSRKSDKKK KGSSNYAYAV TRVRAMKSKL LPKESYPRLL NMGIDEITRF
70 80 90 100 110 120
IQESEYKNDV DELAMKYSGG DLAEHALNRN LALTYDKLVR ITSGELNYLI VAYLKRYDIW
130 140 150 160 170 180
NIKTLLRGKI YNASVEDILE SLIAAGEFTY TSMSELAAKA TYQEIVEALK HTEYYPLLQK
190 200 210 220 230 240
FDGTNLAYIE NELDKIYYAD LFEAIGKPRS KDRKLFAQVV RLEVDVKNLI NLFRLKKAGV
250 260 270 280 290 300
MQPDEIMPLM IEGGLELKIE KLAALPYDEF VNELQRTQYW EAISGVVGPD MISLTTLESR
310 320 330 340 350
LTRYYLESST ILSHVSPITV VPILDYIIHK NNEATNLRII FRGKETGLSD ELIKDQLVII