Q5ZUS2

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
KEGG Pathway
lpn:lpg1720
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

566-635 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5ZUS2

Entry ID Method Resolution Chain Position Source
AF-Q5ZUS2-F1 Predicted AlphaFoldDB

No variants for Q5ZUS2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZUS2

No associated diseases with Q5ZUS2

6 regional properties for Q5ZUS2

Type Name Position InterPro Accession
domain ACT domain 679 - 760 IPR002912-1
domain ACT domain 788 - 861 IPR002912-2
domain HD/PDEase domain 436 - 590 IPR003607
domain Protein-PII uridylyltransferase, N-terminal 22 - 100 IPR005105
domain HD domain 440 - 569 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 166 - 304 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKNDNRIIKN TIKQFKEKLC KDFSQKTNIT SITRKLAVFI DTILIQLFIK NKLHFGDNFC
70 80 90 100 110 120
LLALGSYGRR ELQLHSDIDL LILHTEKVSN IQLQRAQKFI QDCWDVGLEV SHQITTVSSC
130 140 150 160 170 180
ANLASQDLSV ISTIMDMFLL CGHGALMEEL IYQTHTLHMW PSHQYFFAKL QEQQNRYAKY
190 200 210 220 230 240
GETAYNLEPN IKNGPGGLRD LQILLSISKR HFKIKKLAEG IGYGFITDKE YEELKYCQNF
250 260 270 280 290 300
LWRVRFALHM LAGKPEERLS FDYQVKLAQF FGYQDQSHIL AIEQFMKDYF KVIKRNRELN
310 320 330 340 350 360
EMLLQWFNET IVYHQKQKII RLDDEFQLSN RFIEVRNNRV FKQNPQSILK LFYWLVKRPD
370 380 390 400 410 420
IEGVRASTIR LIRESLFLMG KRFRQSKETA NIFINIFRTG NDPYDALQRM NRYGVLAHYL
430 440 450 460 470 480
DCFATVTGQM QYDLFHAYTV DQHTLFVIRN ISRFKKNEYA KQFPLCAKII TALEKPEILY
490 500 510 520 530 540
LGALFHDIAK GRGGDHSELG AIEAQQFTQR HYMEAEDSKL IVWLVRYHLL MSQTAQRKDI
550 560 570 580 590 600
YDPKTIEQFC QLLPHARYLD YLYLLTVADI CGTNPTLWNA WKDSLLKELY HAAKTRLHKQ
610 620 630 640 650 660
QELLDEAALI SIRKQYAMDI LISDGISFRV IQDLWGQFKG KYFLHESPEV IARHTKAILN
670 680 690 700 710 720
SKQFPVVIIM PHHSQGGTEV FIYMPHKDER FTITTSVLSN HHVTIQEAAI ITCDNQFDLD
730 740 750 760 770 780
TYIILDENNQ AFLNEQRARD IQKSLCDHLA NTGRLPAVSR RRLSRALTHF NVKTQINFID
790 800 810 820 830 840
DNTNHQTQLF LVTNDRPGLL ATISRVFLTL NIHLHNAKIA TAGERVEDMF YISNQTGYSL
850 860
NHEEKTILKE KLILEISKSK Y