Q5ZRV4

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
KEGG Pathway
lpn:lpg2772
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

11-310 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q5ZRV4

Entry ID Method Resolution Chain Position Source
AF-Q5ZRV4-F1 Predicted AlphaFoldDB

No variants for Q5ZRV4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q5ZRV4

No associated diseases with Q5ZRV4

7 regional properties for Q5ZRV4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 368 - 537 IPR000795
domain Small GTP-binding protein domain 371 - 527 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 292 - 343 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 62 - 100 IPR013575
domain Translation initiation factor IF- 2, domain 3 644 - 758 IPR023115
domain Translation initiation factor IF-2, domain II 544 - 637 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADVTVKQLA QVVGIPVERL LNQLQEAGLS FTDDQQTVNE EQKRILLNHL KGSSNRDISA
70 80 90 100 110 120
APERITLRRK SMSQVTVGHD MHSGKTVNIE VRKKKTFIKR SAIPEQAEVE EPVVPPVVEE
130 140 150 160 170 180
PVHEEITVVS EVSAETPELK ETEEHPVIEP VAELDETVKE EEKINSEENT AESQDELTHA
190 200 210 220 230 240
NTDVIENLVD VVEETIPVSK KEEVKPEKVS KKKHLEQTDS DISEFKKGKK KPKYHTFEHD
250 260 270 280 290 300
EEEQELHRRG GRSKFKKKKG TEKSDKYREA EETLTHGFAL PTAPIVREVL IPETITVAEL
310 320 330 340 350 360
AKRMSVKAAE VIKVMMSLGA MATINQVIDQ ETSVIVVEEM GHKPIIIKED AVETGLGEAI
370 380 390 400 410 420
SKGTKTEGRA PVVTIMGHVD HGKTSLLDYI RRTKVAAGEA GGITQHIGAY HVSTPKGNIT
430 440 450 460 470 480
FLDTPGHAAF TAMRARGAQA TDIVILIVAA DDGVKPQTIE AIQHAKAAKV PIIVAINKMD
490 500 510 520 530 540
KPDADPERVM NELSVQEVIP EAWGGDTMFV NISAKSGMGI DDLLDAILLQ SEVLELKAVT
550 560 570 580 590 600
DGAAKGVVIE SRLDKGRGPV ATVLVQSGTL HKGDILLAGF QYGRVRALVS DNGDLVDSAG
610 620 630 640 650 660
PSIPVEVLGL SAIPHAGDEA VVVPDEKKAR EVALFRQGRF RDVKLARRQK TTIEGIMENM
670 680 690 700 710 720
TATESKVLNI VLKADVQGSL EAISDALTKL STDEVKVDVI SSGVGGITES DVHLAIASNA
730 740 750 760 770 780
ILIGFNVRAD GTAKRLAEQE SVSIHYYSVI YDIVDQIKGA LTGMLAPQFK EEIVGIAEVR
790 800 810 820 830 840
DVFKSPKIGA IAGCMVIEGV VKRNNPIRVL RSNVVIYEGT LESLRRFKDD VLEVRQGFEC
850 860
GIGVKNYNDV KPGDLIEVFE TVEIKRDL