Q5ZM13
Gene name |
FAM126A (DRCTNNB1A, RCJMB04_3h8) |
Protein name |
Hyccin |
Names |
Down-regulated by CTNNB1 protein A, Protein FAM126A |
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:420611 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ZM13
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ZM13-F1 | Predicted | AlphaFoldDB |
5 variants for Q5ZM13
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs738149988 | 11 | E>G | No | Ensembl | |
| rs735924382 | 389 | A>S | No | Ensembl | |
| rs738556132 | 418 | V>L | No | Ensembl | |
| rs740742425 | 430 | S>P | No | Ensembl | |
| rs314062594 | 487 | G>R | No | Ensembl |
No associated diseases with Q5ZM13
No regional properties for Q5ZM13
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5ZM13 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| myelination | The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. |
| phosphatidylinositol phosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. |
| protein localization to plasma membrane | A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLAVDTGLVE | EWLSEFKTLP | EASISSYATN | LKDKTALISS | LYKVIQEPQS | ELLEPVCHQL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FEFYRSGEEQ | LLRFTLQFLP | ELMWCYLAVS | ASRDLQSSGC | IEALLLGVYN | LEIVDKEGHS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KVLSFTIPSL | SKPSVYHEPS | SIGSMALTEG | ALSQHGLSRV | VYSGPHPQRE | MLTAQNRFEV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTFLLLCYNA | ALSYMPAISL | QSLCQICSRI | CVCGYPRQQV | RKYKGVNSRI | PVSSEFMVQM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTGIYYAFYN | GEWDLARKAM | DDVLYRAQLE | LYPEPLLVAN | AIKASLPQGA | MKSSKEGTKC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IQVEITPTSS | RISRNAVTSM | SIRGHRWKRH | GNADLGIEEE | LIEVSETDEG | FYSRAASSTS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QSALSNSSNT | SSKNLLGKSQ | RRSGGSKAAG | REKEGETCRE | HLSRKQTQRA | LSENLELVSL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KRLTLTTSQS | LPKPGSHSLA | RTTTTVFSKS | FEQVSGVTVA | NNRGGVSGTE | ANRFSACSLQ |
| 490 | 500 | 510 | |||
| EEKLIYGTER | TDLPVLSKQP | NQQRPPSISI | TLSTD |