Q5ZLG3
Gene name |
UTP25 (DEF, DIEXF, RCJMB04_6f17) |
Protein name |
U3 small nucleolar RNA-associated protein 25 homolog |
Names |
Digestive organ expansion factor homolog, UTP25 small subunit processor component |
Species |
Gallus gallus (Chicken) |
KEGG Pathway |
gga:421384 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ZLG3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ZLG3-F1 | Predicted | AlphaFoldDB |
No variants for Q5ZLG3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5ZLG3 | |||||
No associated diseases with Q5ZLG3
No regional properties for Q5ZLG3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q5ZLG3 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| small-subunit processome | A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA binding | Binding to a ribosomal RNA. |
| U3 snoRNA binding | Binding to a U3 small nucleolar RNA. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| embryonic organ development | Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. |
| maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
| positive regulation of embryonic development | Any process that activates or increases the frequency, rate or extent of embryonic development. |
| protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. |
| protein destabilization | Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation. |
| protein localization to nucleolus | A process in which a protein is transported to, or maintained in, a location within a nucleolus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKRRGGREL | ARGLSKRQRK | HLRQFGEQHP | VCDRVSGRPE | ATQICELSDN | SDKSSAESDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ETEVEQVSVY | HKLLATLKAS | PESESEEEED | ESESEEAGES | EAELDSEGSQ | EPKEAVGGEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EQNDVPEQEE | EVAAKDPPEQ | AFGQEEADGV | ETSCDPNRGA | IEEFTDVKHE | AEFSLETNFM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EEESGDCDAD | KRESNSSQAF | SEDPFKQHMD | KELEEKEVEK | ISTLSKTSSQ | SKWPRLGQLT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FSSTLEKHTT | LKPDKEFSVK | QLYLHKPLES | TWPKVNKHYL | SSASKPSDSF | FTPLQRELFC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IMNTYRDLFY | PERNALTNGE | EIRHAYCLHA | LNHILKANAQ | VLSNNAKKRD | QKPGTDSDDY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RDQGLTRPKV | LMIVPFRECA | LRIVHIFISL | LEVNEKRKID | VSNKKRFKGE | FGSDPDEKPP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| NLKRPEDYEA | VFAGNIDDHF | RIGVAILQKS | MRLYAPFYSS | DIIIASPLGM | RTIIGTEGEK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KRDFDFLSSI | EMLIIDQADI | YLMQNWEHVL | HLMRHINLLP | LDSHGVDFSR | VRMPNLNNWS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KYYRQTLLFS | ALQDPQINAI | FNKHCFNYVG | QVAVRNVPLS | GSISRVVVQL | PHVFRRIEAE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| NLTSVIDTRF | QFFIDKVLPE | YRDAIMSHTL | IYVPSYFDYV | RLRNYFKKEE | LNFTHICEYT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KKAGICRARR | SFLKGEKQFL | LLTERFHFYK | RYTIKGIRNL | IFYELPTYSH | FYSEICNMMK |
| 730 | 740 | 750 | 760 | 770 | |
| ATDSGVDATW | TCTVLYSKYD | AQKLAAVVGI | DRTAQMLQSK | KNVHLFVTGE | NE |