Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5ZKR4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5ZKR4-F1 | Predicted | AlphaFoldDB |
No variants for Q5ZKR4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q5ZKR4 | |||||
No associated diseases with Q5ZKR4
1 regional properties for Q5ZKR4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| binding_site | Sigma-54 interaction domain, ATP-binding site 1 | 9 - 22 | IPR025662 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| B cell differentiation | The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. |
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| natural killer cell differentiation | The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell. |
| regulation of protein lipidation | Any process that modulates the frequency, rate or extent of protein lipidation. |
| regulation of Ras protein signal transduction | Any process that modulates the frequency, rate or extent of Ras protein signal transduction. |
| T cell differentiation in thymus | The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1KME6 | RAB6A | Ras-related protein Rab-6A | Gallus gallus (Chicken) | PR |
| Q5ZLG1 | RAB18 | Ras-related protein Rab-18 | Gallus gallus (Chicken) | PR |
| Q6IMM1 | DNAJC27 | DnaJ homolog subfamily C member 27 | Gallus gallus (Chicken) | PR |
| Q6TNS7 | rabl3 | Rab-like protein 3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAALDRVKVL | VLGDSGVGKS | SLVHLLCHNQ | VLGNPSWTVG | CSVDVRIHDY | KEGTPEEKTY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YIELWDVGGS | VGSATSVKST | RAVFYNSLNG | IILVHDLTNK | KSSQNLYRWS | LEALNRDVAP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TGVLVTNGDY | DREQFADNQI | PLLVIGTKLD | QIPETKRNEV | LTRTAFLAED | FNAEEINLDC |
| 190 | 200 | 210 | 220 | ||
| TNPRYLAAGS | SNAVKLSRFF | DKVIEKRYFF | KRWQSRFLAS | RKERDLEEEH |